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- W2415213291 abstract "A patient is presented who used apomorphine, a potent dopamine agonist in the treatment of Parkinson patients. He suffered of severe dystonia of the legs, which did not respond to conservative treatment. The apomorphine was delivered bij intranasal spray. The patient developed an allergic reaction with swollen nose and lips, which disappeared within one day after discontinuation of the treatment. Subcutaneous administration caused no symptoms. Cutaneous challenge with apomorphine caused a positive reaction. We raise the hypothesis that the allergic reaction was due to the binding of apomorphine to certain proteins in cutis or nasal mucosa." @default.
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- W2415213291 date "1992-04-04" @default.
- W2415213291 modified "2023-10-16" @default.
- W2415213291 title "[Nasolabial allergic reaction to intranasal administration of apomorphine in Parkinson disease]." @default.
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