Matches in SemOpenAlex for { <https://semopenalex.org/work/W2415271504> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2415271504 abstract "HIV-infected individuals are at risk for developing certain types of cancers. While there are data to show that non-random HIV integration may occur, our goal was to identify preferential genomic sites where HIV integration might be targeted leading to oncogenesis. Initially, a linker-primer PCR strategy was used to identify HIV integration in isolated macrophages. Inverse-PCR was then used to analyze specimens from patients diagnosed with HIV-associated malignancies. From isolated macrophages, integration near a toll-like receptor on chromosome 4 was found. Necropsy tissues from 11 cases were analyzed with 1 tumor specimen found to have HIV integrated in chromosome 22q13.2 and within 300 kb of HSCBCIP1 (CAP-binding protein complex interacting homologue). Tumor-specific primers were then used to screen uninvolved tissue from the same patient, which did not amplify the site-specific region. This report demonstrates that in both an in vitro system and human malignant tissue, specific viral integration can be identified." @default.
- W2415271504 created "2016-06-24" @default.
- W2415271504 creator A5060291120 @default.
- W2415271504 creator A5061133391 @default.
- W2415271504 creator A5080544101 @default.
- W2415271504 date "2004-01-01" @default.
- W2415271504 modified "2023-10-03" @default.
- W2415271504 title "Preferential HIV-1 integration sites in macrophages and HIV-associated malignancies" @default.
- W2415271504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15555424" @default.
- W2415271504 hasPublicationYear "2004" @default.
- W2415271504 type Work @default.
- W2415271504 sameAs 2415271504 @default.
- W2415271504 citedByCount "4" @default.
- W2415271504 countsByYear W24152715042015 @default.
- W2415271504 crossrefType "journal-article" @default.
- W2415271504 hasAuthorship W2415271504A5060291120 @default.
- W2415271504 hasAuthorship W2415271504A5061133391 @default.
- W2415271504 hasAuthorship W2415271504A5080544101 @default.
- W2415271504 hasConcept C104317684 @default.
- W2415271504 hasConcept C121608353 @default.
- W2415271504 hasConcept C159047783 @default.
- W2415271504 hasConcept C178790620 @default.
- W2415271504 hasConcept C185592680 @default.
- W2415271504 hasConcept C2522874641 @default.
- W2415271504 hasConcept C2777563447 @default.
- W2415271504 hasConcept C2778431562 @default.
- W2415271504 hasConcept C3013748606 @default.
- W2415271504 hasConcept C30481170 @default.
- W2415271504 hasConcept C502942594 @default.
- W2415271504 hasConcept C54355233 @default.
- W2415271504 hasConcept C555283112 @default.
- W2415271504 hasConcept C86803240 @default.
- W2415271504 hasConceptScore W2415271504C104317684 @default.
- W2415271504 hasConceptScore W2415271504C121608353 @default.
- W2415271504 hasConceptScore W2415271504C159047783 @default.
- W2415271504 hasConceptScore W2415271504C178790620 @default.
- W2415271504 hasConceptScore W2415271504C185592680 @default.
- W2415271504 hasConceptScore W2415271504C2522874641 @default.
- W2415271504 hasConceptScore W2415271504C2777563447 @default.
- W2415271504 hasConceptScore W2415271504C2778431562 @default.
- W2415271504 hasConceptScore W2415271504C3013748606 @default.
- W2415271504 hasConceptScore W2415271504C30481170 @default.
- W2415271504 hasConceptScore W2415271504C502942594 @default.
- W2415271504 hasConceptScore W2415271504C54355233 @default.
- W2415271504 hasConceptScore W2415271504C555283112 @default.
- W2415271504 hasConceptScore W2415271504C86803240 @default.
- W2415271504 hasLocation W24152715041 @default.
- W2415271504 hasLocation W24152715042 @default.
- W2415271504 hasOpenAccess W2415271504 @default.
- W2415271504 hasPrimaryLocation W24152715041 @default.
- W2415271504 hasRelatedWork W1996189860 @default.
- W2415271504 hasRelatedWork W2009777127 @default.
- W2415271504 hasRelatedWork W2013361180 @default.
- W2415271504 hasRelatedWork W2033045063 @default.
- W2415271504 hasRelatedWork W2079060747 @default.
- W2415271504 hasRelatedWork W2084823896 @default.
- W2415271504 hasRelatedWork W2110780972 @default.
- W2415271504 hasRelatedWork W2113606923 @default.
- W2415271504 hasRelatedWork W2133139512 @default.
- W2415271504 hasRelatedWork W2136671401 @default.
- W2415271504 hasRelatedWork W2137766006 @default.
- W2415271504 hasRelatedWork W2157438507 @default.
- W2415271504 hasRelatedWork W2390782535 @default.
- W2415271504 hasRelatedWork W2411010126 @default.
- W2415271504 hasRelatedWork W248005853 @default.
- W2415271504 hasRelatedWork W2602545542 @default.
- W2415271504 hasRelatedWork W2606857030 @default.
- W2415271504 hasRelatedWork W3172538314 @default.
- W2415271504 hasRelatedWork W322531675 @default.
- W2415271504 hasRelatedWork W2273556419 @default.
- W2415271504 hasVolume "50" @default.
- W2415271504 isParatext "false" @default.
- W2415271504 isRetracted "false" @default.
- W2415271504 magId "2415271504" @default.
- W2415271504 workType "article" @default.