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• W2415457657 abstract "Perampanel (PER) is the first-in-class selective, noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist that has been licensed and marketed as antiepileptic drug (AED) indicated for patients with partial-onset and primary generalized tonic–clonic seizures. A positive effect was reported in some patients with epileptic myoclonic jerks in idiopathic generalized epilepsy and in progressive myoclonic epilepsy. We treated a male patient with posthypoxic nonepileptic myoclonus (Lance–Adams syndrome) with add-on PER and achieved an almost complete cessation of jerks. This effect was reproducible and, therefore, we suggest that it might be worth trying PER in comparable cases." @default.
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• W2415457657 date "2016-01-01" @default.
• W2415457657 modified "2023-09-23" @default.
• W2415457657 title "Add-on perampanel in Lance–Adams syndrome" @default.
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• W2415457657 doi "https://doi.org/10.1016/j.ebcr.2016.05.001" @default.
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