Matches in SemOpenAlex for { <https://semopenalex.org/work/W2415511343> ?p ?o ?g. }
- W2415511343 endingPage "119" @default.
- W2415511343 startingPage "109" @default.
- W2415511343 abstract "Development of multicellular organisms is commonly associated with the response of individual cells to concentrations of chemical substances called morphogens. Concentration fields of morphogens form a basis for biological patterning and ensure its properties including ability to scale with the size of the organism. While mechanisms underlying the formation of morphogen gradients are reasonably well understood, little is known about processes responsible for their scaling. Here, we perform a formal analysis of scaling for chemical patterns forming in continuous systems. We introduce a quantity representing the sensitivity of systems to changes in their size and use it to analyse scaling properties of patterns forming in a few different systems. Particularly, we consider how scaling properties of morphogen gradients forming in diffusion-decay systems depend on boundary conditions and how the scaling can be improved by passive modulation of morphogens or active transport in the system. We also analyse scaling of morphogenetic signal caused by two opposing gradients and consider scaling properties of patterns forming in activator–inhibitor systems. We conclude with a few possible mechanisms which allow scaling of morphogenetic patterns." @default.
- W2415511343 created "2016-06-24" @default.
- W2415511343 creator A5006290024 @default.
- W2415511343 creator A5063438590 @default.
- W2415511343 date "2016-09-01" @default.
- W2415511343 modified "2023-10-17" @default.
- W2415511343 title "Scaling of morphogenetic patterns in reaction-diffusion systems" @default.
- W2415511343 cites W1572671086 @default.
- W2415511343 cites W1966372396 @default.
- W2415511343 cites W1975982688 @default.
- W2415511343 cites W1982088462 @default.
- W2415511343 cites W1993217285 @default.
- W2415511343 cites W1997132344 @default.
- W2415511343 cites W1998586550 @default.
- W2415511343 cites W2013424580 @default.
- W2415511343 cites W2016276230 @default.
- W2415511343 cites W2016350172 @default.
- W2415511343 cites W2019562739 @default.
- W2415511343 cites W2026211608 @default.
- W2415511343 cites W2028541846 @default.
- W2415511343 cites W2036828218 @default.
- W2415511343 cites W2059418130 @default.
- W2415511343 cites W2084694304 @default.
- W2415511343 cites W2086441427 @default.
- W2415511343 cites W2087859062 @default.
- W2415511343 cites W2095220792 @default.
- W2415511343 cites W2100898236 @default.
- W2415511343 cites W2115050888 @default.
- W2415511343 cites W2115609201 @default.
- W2415511343 cites W2126664377 @default.
- W2415511343 cites W2127071442 @default.
- W2415511343 cites W2128584428 @default.
- W2415511343 cites W2138336686 @default.
- W2415511343 cites W2142801207 @default.
- W2415511343 cites W2143368326 @default.
- W2415511343 cites W2144762520 @default.
- W2415511343 cites W2161045785 @default.
- W2415511343 cites W2171005709 @default.
- W2415511343 cites W2332359596 @default.
- W2415511343 cites W4250716583 @default.
- W2415511343 cites W72928827 @default.
- W2415511343 doi "https://doi.org/10.1016/j.jtbi.2016.05.035" @default.
- W2415511343 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4956305" @default.
- W2415511343 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27255960" @default.
- W2415511343 hasPublicationYear "2016" @default.
- W2415511343 type Work @default.
- W2415511343 sameAs 2415511343 @default.
- W2415511343 citedByCount "9" @default.
- W2415511343 countsByYear W24155113432018 @default.
- W2415511343 countsByYear W24155113432019 @default.
- W2415511343 countsByYear W24155113432021 @default.
- W2415511343 countsByYear W24155113432022 @default.
- W2415511343 countsByYear W24155113432023 @default.
- W2415511343 crossrefType "journal-article" @default.
- W2415511343 hasAuthorship W2415511343A5006290024 @default.
- W2415511343 hasAuthorship W2415511343A5063438590 @default.
- W2415511343 hasBestOaLocation W24155113431 @default.
- W2415511343 hasConcept C104317684 @default.
- W2415511343 hasConcept C121332964 @default.
- W2415511343 hasConcept C186060115 @default.
- W2415511343 hasConcept C207016750 @default.
- W2415511343 hasConcept C2524010 @default.
- W2415511343 hasConcept C2778386714 @default.
- W2415511343 hasConcept C33923547 @default.
- W2415511343 hasConcept C54355233 @default.
- W2415511343 hasConcept C69357855 @default.
- W2415511343 hasConcept C74318829 @default.
- W2415511343 hasConcept C86803240 @default.
- W2415511343 hasConcept C97355855 @default.
- W2415511343 hasConcept C99844830 @default.
- W2415511343 hasConceptScore W2415511343C104317684 @default.
- W2415511343 hasConceptScore W2415511343C121332964 @default.
- W2415511343 hasConceptScore W2415511343C186060115 @default.
- W2415511343 hasConceptScore W2415511343C207016750 @default.
- W2415511343 hasConceptScore W2415511343C2524010 @default.
- W2415511343 hasConceptScore W2415511343C2778386714 @default.
- W2415511343 hasConceptScore W2415511343C33923547 @default.
- W2415511343 hasConceptScore W2415511343C54355233 @default.
- W2415511343 hasConceptScore W2415511343C69357855 @default.
- W2415511343 hasConceptScore W2415511343C74318829 @default.
- W2415511343 hasConceptScore W2415511343C86803240 @default.
- W2415511343 hasConceptScore W2415511343C97355855 @default.
- W2415511343 hasConceptScore W2415511343C99844830 @default.
- W2415511343 hasFunder F4320334627 @default.
- W2415511343 hasFunder F4320334629 @default.
- W2415511343 hasLocation W24155113431 @default.
- W2415511343 hasLocation W24155113432 @default.
- W2415511343 hasLocation W24155113433 @default.
- W2415511343 hasLocation W24155113434 @default.
- W2415511343 hasOpenAccess W2415511343 @default.
- W2415511343 hasPrimaryLocation W24155113431 @default.
- W2415511343 hasRelatedWork W1578507486 @default.
- W2415511343 hasRelatedWork W2070367039 @default.
- W2415511343 hasRelatedWork W2089390657 @default.
- W2415511343 hasRelatedWork W2094954504 @default.
- W2415511343 hasRelatedWork W2167834648 @default.
- W2415511343 hasRelatedWork W2511616590 @default.
- W2415511343 hasRelatedWork W2902269078 @default.