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- W2415663044 abstract "The reasons for patients to change their usual vitamin K antagonist (VKA) treatment to a direct oral anticoagulant (DOAC) are unexplored.A random sample of 200 patients treated with VKAs for the indication of atrial fibrillation from the Thrombosis Service in Amsterdam was selected. A survey, using the treatment trade-off technique, was sent to participants. The trade-off included four scenarios: 1 (no need for laboratory controls); 2 (less bleeding); 3 (less interactions); 4 (more effective).Under scenario 1, 57% of the patients would have made the switch, with a further increase to 65% with scenario 2 (trend value, p = 0.006, 95% CI 1.11-1.85). In addition, in each scenario patients who were less satisfied with their current treatment were more likely to switch to a DOAC compared with satisfied patients. The variables duration of treatment, gender, age and educational level did not affect the preference for a DOAC.Patients considered no requirement for regular laboratory control and a lower risk of bleeding the most important arguments to switch to a DOAC." @default.
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- W2415663044 date "2015-10-01" @default.
- W2415663044 modified "2023-09-23" @default.
- W2415663044 title "When do patients prefer a direct oral anticoagulant over a vitamin K antagonist?" @default.
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