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- W2415666733 abstract "From Dec. 1982 to Oct. 1984, 35 patients with SCLC proved by pathology or cytology, were treated by cyclophosphamide + methotrexate + CCNU (CMC) regimen combined with surgery in our hospital. All the patients received chemotherapy for more than 2 courses and the overall response rate was 85.7%, complete remission (CR) rate was 14.3%. Toxic reactions were tolerable to the patients. Treatment result was better in SCLC with localized than extensive disease. Operation was done for 9 out of 21 patients with localized lesions which had responded to chemotherapy. Of them, 1 died of postoperative complication, 2 were lost in follow-up and the rest 6 were disease-free for 8-32 months with a median survival time of 19 months. The 1 year survival rate was 75%. The results indicate that in limited disease of SCLC, successful chemotherapy combined with surgery can prolong the survival time. For patients with an limited disease which has given a CR, surgical resection should be strived for." @default.
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- W2415666733 date "1986-11-01" @default.
- W2415666733 modified "2023-09-23" @default.
- W2415666733 title "[CMC chemotherapy regimen combined with surgery of small cell lung cancer (SCLC)]." @default.
- W2415666733 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3034537" @default.
- W2415666733 hasPublicationYear "1986" @default.
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