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- W2415693029 abstract "Gliomatosis cerebri (GC) is a rare and highly aggressive malignancy with no known effective treatment. It is characterized as a diffuse glial tumor affecting at least three cerebral lobes. While radiation therapy has been considered to be the standard of care for initial treatment, it can often lead to significant neuro-toxicity and a survival benefit has not been clinically proven. I present the case of a 50 year old man with GC treated with temozolomide and concurrent, continuous tumor treating fields via the Optune device. Radiation therapy has been deferred in his case. After more than a year of treatment, he has continued to experience a positive clinical and radiographic response to this treatment regimen. Details of his case, including imaging findings, are presented. A clinical trial evaluating this treatment strategy for GC is being planned." @default.
- W2415693029 created "2016-06-24" @default.
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- W2415693029 date "2015-11-01" @default.
- W2415693029 modified "2023-09-28" @default.
- W2415693029 title "ATCT-06MANAGEMENT OF GLIOMATOSIS CEREBRI WITH TEMOZOLOMIDE AND TUMOR TREATING FIELDS" @default.
- W2415693029 doi "https://doi.org/10.1093/neuonc/nov206.06" @default.
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