Matches in SemOpenAlex for { <https://semopenalex.org/work/W2415693345> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2415693345 endingPage "92" @default.
- W2415693345 startingPage "589" @default.
- W2415693345 abstract "Mycoplasma pneumoniae, M. gallisepticum and M. pulmonis are pathogens of the respiratory tract. Their adherence to the host tissue is a prerequisite for manifestation of the disease. The attachment occurs between membrane components of the mycoplasmas and the host cells. In the attachment of M. pneumoniae and M. gallisepticum, binding sites of a protein nature of the mycoplasma membranes interact primarily with sialic acid residues of sialoglycoproteins of the host cell membranes. The latter was clearly indicated in studies on the pathogenic strain of M. pneumoniae and its nonpathogenic nonhemadsorbing mutants, and by the assessment of the direct binding of glycophorin [the major sialoglycoprotein of human red blood cells (RBC)] and other sialoglycoproteins to M. pneumoniae and M. gallisepticum. The components involved in the interaction of M. pulmonis with the host cells are not as well characterized, since the attachment is not affected by proteolytic treatment of the mycoplasmas, nor by removal of sialic acid residues from the host cell membranes. The attachment of the mycoplasmas to the host cells also occurs with nonviable organisms and can, in addition, by reproduced by isolated membranes. The binding sites of M. pneumoniae and M. gallisepticum were partially purified by affinity chromatography, using the high affinity of the binding sites for glycophorin. By this procedure the membranes were solubilized with detergents and chromatographed through glycophorin attached to Sepharose 4B as an affinity matrix. The binding sites retained the high affinity for glycophorin and bound to RBC membranes. Are the binding sites distributed throughout the membrane? Since the binding of the mycoplasma is via a polar structure (the tip or bleb), one may suggest that these structures harbor them. Experimental evidence for their distribution is being sought." @default.
- W2415693345 created "2016-06-24" @default.
- W2415693345 creator A5001716170 @default.
- W2415693345 creator A5033850007 @default.
- W2415693345 creator A5059284440 @default.
- W2415693345 creator A5067450658 @default.
- W2415693345 creator A5067957137 @default.
- W2415693345 creator A5091319474 @default.
- W2415693345 date "1981-07-01" @default.
- W2415693345 modified "2023-09-23" @default.
- W2415693345 title "Attachment of mycoplasmas to erythrocytes: a model to study mycoplasma attachment to the epithelium of the host respiratory tract." @default.
- W2415693345 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7287399" @default.
- W2415693345 hasPublicationYear "1981" @default.
- W2415693345 type Work @default.
- W2415693345 sameAs 2415693345 @default.
- W2415693345 citedByCount "6" @default.
- W2415693345 countsByYear W24156933452018 @default.
- W2415693345 crossrefType "journal-article" @default.
- W2415693345 hasAuthorship W2415693345A5001716170 @default.
- W2415693345 hasAuthorship W2415693345A5033850007 @default.
- W2415693345 hasAuthorship W2415693345A5059284440 @default.
- W2415693345 hasAuthorship W2415693345A5067450658 @default.
- W2415693345 hasAuthorship W2415693345A5067957137 @default.
- W2415693345 hasAuthorship W2415693345A5091319474 @default.
- W2415693345 hasConcept C126322002 @default.
- W2415693345 hasConcept C179247698 @default.
- W2415693345 hasConcept C181199279 @default.
- W2415693345 hasConcept C2776178622 @default.
- W2415693345 hasConcept C2777914695 @default.
- W2415693345 hasConcept C2778838687 @default.
- W2415693345 hasConcept C2779215961 @default.
- W2415693345 hasConcept C2780115458 @default.
- W2415693345 hasConcept C2781151156 @default.
- W2415693345 hasConcept C2909850280 @default.
- W2415693345 hasConcept C41625074 @default.
- W2415693345 hasConcept C55493867 @default.
- W2415693345 hasConcept C67982717 @default.
- W2415693345 hasConcept C71924100 @default.
- W2415693345 hasConcept C86803240 @default.
- W2415693345 hasConcept C89423630 @default.
- W2415693345 hasConceptScore W2415693345C126322002 @default.
- W2415693345 hasConceptScore W2415693345C179247698 @default.
- W2415693345 hasConceptScore W2415693345C181199279 @default.
- W2415693345 hasConceptScore W2415693345C2776178622 @default.
- W2415693345 hasConceptScore W2415693345C2777914695 @default.
- W2415693345 hasConceptScore W2415693345C2778838687 @default.
- W2415693345 hasConceptScore W2415693345C2779215961 @default.
- W2415693345 hasConceptScore W2415693345C2780115458 @default.
- W2415693345 hasConceptScore W2415693345C2781151156 @default.
- W2415693345 hasConceptScore W2415693345C2909850280 @default.
- W2415693345 hasConceptScore W2415693345C41625074 @default.
- W2415693345 hasConceptScore W2415693345C55493867 @default.
- W2415693345 hasConceptScore W2415693345C67982717 @default.
- W2415693345 hasConceptScore W2415693345C71924100 @default.
- W2415693345 hasConceptScore W2415693345C86803240 @default.
- W2415693345 hasConceptScore W2415693345C89423630 @default.
- W2415693345 hasIssue "7" @default.
- W2415693345 hasLocation W24156933451 @default.
- W2415693345 hasOpenAccess W2415693345 @default.
- W2415693345 hasPrimaryLocation W24156933451 @default.
- W2415693345 hasRelatedWork W1511913702 @default.
- W2415693345 hasRelatedWork W1536317151 @default.
- W2415693345 hasRelatedWork W1957157899 @default.
- W2415693345 hasRelatedWork W1965301250 @default.
- W2415693345 hasRelatedWork W2031660131 @default.
- W2415693345 hasRelatedWork W2080335382 @default.
- W2415693345 hasRelatedWork W2140666762 @default.
- W2415693345 hasRelatedWork W2146275508 @default.
- W2415693345 hasRelatedWork W2414161354 @default.
- W2415693345 hasRelatedWork W2415693345 @default.
- W2415693345 hasVolume "17" @default.
- W2415693345 isParatext "false" @default.
- W2415693345 isRetracted "false" @default.
- W2415693345 magId "2415693345" @default.
- W2415693345 workType "article" @default.