Matches in SemOpenAlex for { <https://semopenalex.org/work/W2415705911> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2415705911 endingPage "6" @default.
- W2415705911 startingPage "1" @default.
- W2415705911 abstract "In serum and in cerebrospinal fluid (CSF) from patients with human African trypanosomiasis (HAT) with central nervous system involvement, we detected autoantibodies directed to some proteins from these tissues. The characterization of antigenic proteins by Western blotting showed that the antibodies recognized the 200-kD and 160-kD proteins of neurofilament (NF). Serum anti-NF antibodies were more frequent in HAT patients than in control subjects (86% versus 24%; P < 10[-9]) and they belonged predominantly to the IgM class (anti-NF IgM = 86% versus anti-NF IgG = 4%; P < 10[-9]) in the patients with stage II (central nervous system involvement) HAT. The CSF antibodies to NF were IgM in 88% (22 of 25) of the cases and IgG in 32% (8 of 25) of the cases. Epitopes shared by NF and trypanosomes were detected by indirect immunofluorescence and this was confirmed by the disappearance of anti-NF reactivity after adsorption with trypanosome antigens (Trypanosoma brucei brucei or T. b. gambiense). Anti-NF antibodies were undetectable in the CSF from stage I HAT patients." @default.
- W2415705911 created "2016-06-24" @default.
- W2415705911 creator A5008044210 @default.
- W2415705911 creator A5012920975 @default.
- W2415705911 creator A5017043364 @default.
- W2415705911 creator A5029713442 @default.
- W2415705911 creator A5039102579 @default.
- W2415705911 creator A5040030287 @default.
- W2415705911 creator A5052313114 @default.
- W2415705911 creator A5085902260 @default.
- W2415705911 date "1997-07-01" @default.
- W2415705911 modified "2023-10-17" @default.
- W2415705911 title "Detection and characterization of autoantibodies directed against neurofilament proteins in human African trypanosomiasis." @default.
- W2415705911 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9242309" @default.
- W2415705911 hasPublicationYear "1997" @default.
- W2415705911 type Work @default.
- W2415705911 sameAs 2415705911 @default.
- W2415705911 citedByCount "20" @default.
- W2415705911 countsByYear W24157059112012 @default.
- W2415705911 countsByYear W24157059112013 @default.
- W2415705911 countsByYear W24157059112014 @default.
- W2415705911 countsByYear W24157059112015 @default.
- W2415705911 countsByYear W24157059112019 @default.
- W2415705911 crossrefType "journal-article" @default.
- W2415705911 hasAuthorship W2415705911A5008044210 @default.
- W2415705911 hasAuthorship W2415705911A5012920975 @default.
- W2415705911 hasAuthorship W2415705911A5017043364 @default.
- W2415705911 hasAuthorship W2415705911A5029713442 @default.
- W2415705911 hasAuthorship W2415705911A5039102579 @default.
- W2415705911 hasAuthorship W2415705911A5040030287 @default.
- W2415705911 hasAuthorship W2415705911A5052313114 @default.
- W2415705911 hasAuthorship W2415705911A5085902260 @default.
- W2415705911 hasConcept C104317684 @default.
- W2415705911 hasConcept C147483822 @default.
- W2415705911 hasConcept C153911025 @default.
- W2415705911 hasConcept C157207234 @default.
- W2415705911 hasConcept C159047783 @default.
- W2415705911 hasConcept C159654299 @default.
- W2415705911 hasConcept C163764329 @default.
- W2415705911 hasConcept C169760540 @default.
- W2415705911 hasConcept C195616568 @default.
- W2415705911 hasConcept C203014093 @default.
- W2415705911 hasConcept C204232928 @default.
- W2415705911 hasConcept C2778143080 @default.
- W2415705911 hasConcept C2778236600 @default.
- W2415705911 hasConcept C2778792689 @default.
- W2415705911 hasConcept C2779502636 @default.
- W2415705911 hasConcept C2779651940 @default.
- W2415705911 hasConcept C55493867 @default.
- W2415705911 hasConcept C85265743 @default.
- W2415705911 hasConcept C86803240 @default.
- W2415705911 hasConceptScore W2415705911C104317684 @default.
- W2415705911 hasConceptScore W2415705911C147483822 @default.
- W2415705911 hasConceptScore W2415705911C153911025 @default.
- W2415705911 hasConceptScore W2415705911C157207234 @default.
- W2415705911 hasConceptScore W2415705911C159047783 @default.
- W2415705911 hasConceptScore W2415705911C159654299 @default.
- W2415705911 hasConceptScore W2415705911C163764329 @default.
- W2415705911 hasConceptScore W2415705911C169760540 @default.
- W2415705911 hasConceptScore W2415705911C195616568 @default.
- W2415705911 hasConceptScore W2415705911C203014093 @default.
- W2415705911 hasConceptScore W2415705911C204232928 @default.
- W2415705911 hasConceptScore W2415705911C2778143080 @default.
- W2415705911 hasConceptScore W2415705911C2778236600 @default.
- W2415705911 hasConceptScore W2415705911C2778792689 @default.
- W2415705911 hasConceptScore W2415705911C2779502636 @default.
- W2415705911 hasConceptScore W2415705911C2779651940 @default.
- W2415705911 hasConceptScore W2415705911C55493867 @default.
- W2415705911 hasConceptScore W2415705911C85265743 @default.
- W2415705911 hasConceptScore W2415705911C86803240 @default.
- W2415705911 hasIssue "1" @default.
- W2415705911 hasLocation W24157059111 @default.
- W2415705911 hasOpenAccess W2415705911 @default.
- W2415705911 hasPrimaryLocation W24157059111 @default.
- W2415705911 hasRelatedWork W1982194517 @default.
- W2415705911 hasRelatedWork W2026717219 @default.
- W2415705911 hasRelatedWork W2031788227 @default.
- W2415705911 hasRelatedWork W2077845129 @default.
- W2415705911 hasRelatedWork W2079379472 @default.
- W2415705911 hasRelatedWork W2079908027 @default.
- W2415705911 hasRelatedWork W2081721927 @default.
- W2415705911 hasRelatedWork W2094253331 @default.
- W2415705911 hasRelatedWork W2152488232 @default.
- W2415705911 hasRelatedWork W2415705911 @default.
- W2415705911 hasVolume "57" @default.
- W2415705911 isParatext "false" @default.
- W2415705911 isRetracted "false" @default.
- W2415705911 magId "2415705911" @default.
- W2415705911 workType "article" @default.