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- W2415721871 abstract "Kainic acid (KA) caused an initial decrease and a subsequent rebound in hippocampal enkephalin (ENK) in rats exhibiting wet dog shakes (WDS) without behavioral convulsions. Antibody to methionine-enkephalin but not dynorphin A(1-8) injected into lateral ventricles attenuated KA-induced WDS, as did naloxone. Granule-cell destroying injections of colchicine into ventral but not dorsal hippocampus caused a 60% reduction of hippocampal ENK and a complete elimination of KA-induced WDS. These studies suggest that release of granule cell ENK, which is 3 times more concentrated in ventral than dorsal hippocampus, plays an important role in KA-induced WDS." @default.
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- W2415721871 date "1986-01-01" @default.
- W2415721871 modified "2023-09-25" @default.
- W2415721871 title "Enkephalin contained in dentate granule cells is important for kainic acid-induced wet dog shakes." @default.
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