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- W24157250 abstract "DCE-MR breast imaging is becoming an important modality as a problem-solving tool and in screening of high-risk patients. In DCE-MR a T1-weighted time series is recorded during the uptake of a contrast agent (CA: Gd-DTPA) that enables the assessment of voxel-specific dynamic tissue properties. Tumor malignancy often goes hand in hand with high vascularity and high vessel wall permeability because of angiogenesis; i.e. a large number of new vessels is formed at such a rate that their walls are not properly constructed and therefore highly permeable. These ‘malignant’ tissue characteristics affect the shape of the CA-uptake curve. The goal is to investigate the use of a pharmacokinetic twocompartment model (extended Kety [1]) in the context of dynamic analysis of CA-uptake curves as a contribution to automatic detection and characterization of breast cancer." @default.
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- W24157250 date "2007-01-01" @default.
- W24157250 modified "2023-09-26" @default.
- W24157250 title "Pharmacokinetic analysis of dynamic contrast-enhanced (DCE) MR breast images" @default.
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