Matches in SemOpenAlex for { <https://semopenalex.org/work/W2415832521> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W2415832521 endingPage "67" @default.
- W2415832521 startingPage "56" @default.
- W2415832521 abstract "Highly specialized, state-of-the-art diagnostic tests are available for identifying congenital and acquired immune defects. These methods should only be resorted to when less complicated means have created suspicion of an immune defect. The case history, including the family history, represents the core of the diagnostic procedure. Initially, only simple clinical investigations are indicated. These should enable the physician to exclude or delimit a defect in the immune system which then can be defined more closely by specific tests. Screening includes clinical chemistry (erythrocyte sedimentation rate, total serum protein, serum electrophoresis, C-reactive protein, blood count including differential blood count, ferritin, urine analysis, and a quantitative assay of the immunoglobulins A, G and M), bacteriological, serological, and radiological investigations, and finally skin tests with recall antigens. Thereby, it is usually possible to reliably detect primary B cell defects with humoral antibody deficiency syndromes. Lymphocyte subset counts, immunoelectrophoresis, and bone marrow biopsy are necessary for the differential diagnosis, or for the confirmation, of malignant lymphatic proliferation, especially in adults. IgG subclass defects as well as granulocyte dysfunction and complement defects must be excluded in patients who are susceptible to bacterial infection despite normal immunoglobulin concentrations. In suspected cases of primary or secondary (HIV, cytomegalovirus, Epstein-Barr virus) T cell defects, lymphocyte subset counts and, where applicable, T cell function tests are indicated. The majority of secondary immunodeficiency syndromes, in which the primary disease is known, do not currently require specialized diagnosis. Nevertheless, monitoring of the lymphocyte subsets in HIV-positive patients has already become standard practice in health care (for evaluating the prognosis and deciding on the therapy)." @default.
- W2415832521 created "2016-06-24" @default.
- W2415832521 creator A5021206356 @default.
- W2415832521 creator A5046956541 @default.
- W2415832521 date "1993-04-01" @default.
- W2415832521 modified "2023-09-23" @default.
- W2415832521 title "[Laboratory diagnosis of immune deficiency]." @default.
- W2415832521 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8499752" @default.
- W2415832521 hasPublicationYear "1993" @default.
- W2415832521 type Work @default.
- W2415832521 sameAs 2415832521 @default.
- W2415832521 citedByCount "0" @default.
- W2415832521 crossrefType "journal-article" @default.
- W2415832521 hasAuthorship W2415832521A5021206356 @default.
- W2415832521 hasAuthorship W2415832521A5046956541 @default.
- W2415832521 hasConcept C142724271 @default.
- W2415832521 hasConcept C159654299 @default.
- W2415832521 hasConcept C203014093 @default.
- W2415832521 hasConcept C2777607303 @default.
- W2415832521 hasConcept C2777761686 @default.
- W2415832521 hasConcept C2779019163 @default.
- W2415832521 hasConcept C2780801072 @default.
- W2415832521 hasConcept C45189115 @default.
- W2415832521 hasConcept C71924100 @default.
- W2415832521 hasConcept C86803240 @default.
- W2415832521 hasConcept C8891405 @default.
- W2415832521 hasConceptScore W2415832521C142724271 @default.
- W2415832521 hasConceptScore W2415832521C159654299 @default.
- W2415832521 hasConceptScore W2415832521C203014093 @default.
- W2415832521 hasConceptScore W2415832521C2777607303 @default.
- W2415832521 hasConceptScore W2415832521C2777761686 @default.
- W2415832521 hasConceptScore W2415832521C2779019163 @default.
- W2415832521 hasConceptScore W2415832521C2780801072 @default.
- W2415832521 hasConceptScore W2415832521C45189115 @default.
- W2415832521 hasConceptScore W2415832521C71924100 @default.
- W2415832521 hasConceptScore W2415832521C86803240 @default.
- W2415832521 hasConceptScore W2415832521C8891405 @default.
- W2415832521 hasLocation W24158325211 @default.
- W2415832521 hasOpenAccess W2415832521 @default.
- W2415832521 hasPrimaryLocation W24158325211 @default.
- W2415832521 hasRelatedWork W1510504641 @default.
- W2415832521 hasRelatedWork W1583531858 @default.
- W2415832521 hasRelatedWork W1859477696 @default.
- W2415832521 hasRelatedWork W1907388817 @default.
- W2415832521 hasRelatedWork W2067264463 @default.
- W2415832521 hasRelatedWork W2068537085 @default.
- W2415832521 hasRelatedWork W2084801194 @default.
- W2415832521 hasRelatedWork W2318932960 @default.
- W2415832521 hasRelatedWork W2808922063 @default.
- W2415832521 hasRelatedWork W4237664858 @default.
- W2415832521 hasVolume "20 Suppl 1" @default.
- W2415832521 isParatext "false" @default.
- W2415832521 isRetracted "false" @default.
- W2415832521 magId "2415832521" @default.
- W2415832521 workType "article" @default.