Matches in SemOpenAlex for { <https://semopenalex.org/work/W2415939087> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2415939087 endingPage "61" @default.
- W2415939087 startingPage "156" @default.
- W2415939087 abstract "Comparison of two methods of irradiation of patients with malignant choroidal melanoma - stereotactic radiosurgery and proton beam irradiation. External (non-contact) applied irradiation is used as a source of accelerated protons, respectively helium ions. This method allows applications of ionizing irradiation also despite the low radiosensitivity of cells of malignant melanoma of the uvea (MMU). External source of ionizing radiation is modulated current energy electrons, protons or neutrons, accelerated in linear accelerators. From the external medium voltages resources (4-16 MeV) are irradiated tissues with target dose of 5.0-24.0 Gy. Volume protons permeate straight the structures of the eye to a certain distance. The use of proton radiation density of ionized protons increases in the vicinity of the impact due to energy losses for electrons interacting with the environment. At the end of the track there is a huge increase in the ionization dose (Bragg spike). Therefore, the structures surrounding the eye at the point of entry and little affected and increasing the dose at the end of the proton beam is ideal for the desired therapeutic effect. Fractionated application is also possible.In December 2011 we performed stereotactic radiosurgery to treat female patient (born 1939) with malignant melanoma of the choroid stage T1 N0 M0. Plan has been drawn up for stereotactic irradiation - model for linear accelerator Clinac, Corvus planning system ver. 6.2, verification and OmniPro IMRT planning system Liebinger ver. 4.3. Patient characteristics were compared with the virtual plan for proton radiation therapy, and we used the scheme in Physical parameters FIAN-technical center in the Russian Federation. We compared both planning protocols and assess in particular the extent of radiation surrounding non-tumor tissue.When comparing the two planning schemes irradiation levels of surrounding tissues and risk structures (lens, optic nerve, chiasm) in both methods were corresponding to the required standard.Treatment of uveal melanoma through proton beam irradiation in Slovakia is not available yet, although it has several advantages, such as fractionation and the possibility of achieving a higher dose of irradiation to deposit (more than 50.0 Gy). The fundamental difference between the two methods for an eye is particularly the possibility of proton beam irradiation exposure of tumor of iris and ciliary body, which can not be solved through stereotactic radiosurgery. The dose to the tumor during irradiation can be optimized. The model device allowed us to make OPTMI - Therapy (Proton Treatment with Optimized Modulated Intensity)." @default.
- W2415939087 created "2016-06-24" @default.
- W2415939087 creator A5002953046 @default.
- W2415939087 creator A5006208966 @default.
- W2415939087 creator A5034558794 @default.
- W2415939087 creator A5064579820 @default.
- W2415939087 creator A5079568370 @default.
- W2415939087 creator A5091722332 @default.
- W2415939087 date "2012-10-01" @default.
- W2415939087 modified "2023-10-18" @default.
- W2415939087 title "[Choroidal melanoma stage T1 - comparison of the planning protocol for stereotactic radiosurgery and proton beam irradiation]." @default.
- W2415939087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23214488" @default.
- W2415939087 hasPublicationYear "2012" @default.
- W2415939087 type Work @default.
- W2415939087 sameAs 2415939087 @default.
- W2415939087 citedByCount "0" @default.
- W2415939087 crossrefType "journal-article" @default.
- W2415939087 hasAuthorship W2415939087A5002953046 @default.
- W2415939087 hasAuthorship W2415939087A5006208966 @default.
- W2415939087 hasAuthorship W2415939087A5034558794 @default.
- W2415939087 hasAuthorship W2415939087A5064579820 @default.
- W2415939087 hasAuthorship W2415939087A5079568370 @default.
- W2415939087 hasAuthorship W2415939087A5091722332 @default.
- W2415939087 hasConcept C111337013 @default.
- W2415939087 hasConcept C120665830 @default.
- W2415939087 hasConcept C121332964 @default.
- W2415939087 hasConcept C126838900 @default.
- W2415939087 hasConcept C168834538 @default.
- W2415939087 hasConcept C18231593 @default.
- W2415939087 hasConcept C185544564 @default.
- W2415939087 hasConcept C2778418280 @default.
- W2415939087 hasConcept C2779244869 @default.
- W2415939087 hasConcept C2780387249 @default.
- W2415939087 hasConcept C2989005 @default.
- W2415939087 hasConcept C509974204 @default.
- W2415939087 hasConcept C54516573 @default.
- W2415939087 hasConcept C71924100 @default.
- W2415939087 hasConceptScore W2415939087C111337013 @default.
- W2415939087 hasConceptScore W2415939087C120665830 @default.
- W2415939087 hasConceptScore W2415939087C121332964 @default.
- W2415939087 hasConceptScore W2415939087C126838900 @default.
- W2415939087 hasConceptScore W2415939087C168834538 @default.
- W2415939087 hasConceptScore W2415939087C18231593 @default.
- W2415939087 hasConceptScore W2415939087C185544564 @default.
- W2415939087 hasConceptScore W2415939087C2778418280 @default.
- W2415939087 hasConceptScore W2415939087C2779244869 @default.
- W2415939087 hasConceptScore W2415939087C2780387249 @default.
- W2415939087 hasConceptScore W2415939087C2989005 @default.
- W2415939087 hasConceptScore W2415939087C509974204 @default.
- W2415939087 hasConceptScore W2415939087C54516573 @default.
- W2415939087 hasConceptScore W2415939087C71924100 @default.
- W2415939087 hasIssue "4" @default.
- W2415939087 hasLocation W24159390871 @default.
- W2415939087 hasOpenAccess W2415939087 @default.
- W2415939087 hasPrimaryLocation W24159390871 @default.
- W2415939087 hasRelatedWork W2167624373 @default.
- W2415939087 hasRelatedWork W2408625789 @default.
- W2415939087 hasRelatedWork W2557556302 @default.
- W2415939087 hasRelatedWork W2747322794 @default.
- W2415939087 hasRelatedWork W2901819744 @default.
- W2415939087 hasRelatedWork W3092451929 @default.
- W2415939087 hasRelatedWork W3102344862 @default.
- W2415939087 hasRelatedWork W3118418136 @default.
- W2415939087 hasRelatedWork W3166006814 @default.
- W2415939087 hasRelatedWork W4288083030 @default.
- W2415939087 hasVolume "68" @default.
- W2415939087 isParatext "false" @default.
- W2415939087 isRetracted "false" @default.
- W2415939087 magId "2415939087" @default.
- W2415939087 workType "article" @default.