Matches in SemOpenAlex for { <https://semopenalex.org/work/W2416004425> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2416004425 endingPage "21" @default.
- W2416004425 startingPage "117" @default.
- W2416004425 abstract "The highest incidence of anaplastic thyroid carcinoma (ATC) has been reported in countries with endemic goiter, such as in Ecuador. In this country, ATC is the third most common histologic type of thyroid cancer, following papillary and follicular carcinoma. The aim of this study was to review the clinical presentation and the results of treatment of a large consecutive series of ATC patients treated at the oncological department of a general hospital in Quito, Ecuador. This is a retrospective study of 30 patients diagnosed with ATC at the Social Security Hospital, from 1982 to 1998. Symptomatic rapidly growing neck masses were generally present. All the patients had histological diagnosis of ATC. Two patients with pulmonary metastases and pleural effusion died before treatment could be instituted. Twenty-eight patients received at least one type of treatment: surgery, radiation therapy (RT), or chemotherapy (CT). The two most frequently employed therapeutic modalities were surgery followed by RT and/or CT in 14 patients and surgery alone in 9 patients. Surgery was performed in 23 patients but a complete resection was possible in only 14 patients. RT, postoperatively or alone, was given to 17 patients. Only 5 patients received doses ranging from 4,000 to 5,000 cGy and 4 patients more than 5,000 cGy. CT was administered to 17 patients. Doxorubicin alone was given to 10 patients and different combinations to the remaining patients. Local control was obtained in 8 of 14 complete resections. The prognostic value of the following parameters was studied by univariate analysis: duration of symptoms, size of the tumor, extent of glandular involvement, type of treatment, and surgical margins. A statistically longer survival was found in cases of differentiated carcinoma with areas of ATC or tumor limited to one lobe, those patients who received a complete treatment of chemotherapy, and those patients with tumors smaller than 10 cm and with duration of symptoms longer than 4 months. Longer mean survivals were seen in patients with longer duration of symptoms and smaller lesions. Five patients with focal anaplastic lesions within a differentiated thyroid carcinoma or a lesion limited to one lobe had a significant better survival (a mean of 20 months)." @default.
- W2416004425 created "2016-06-24" @default.
- W2416004425 creator A5005345650 @default.
- W2416004425 creator A5045726331 @default.
- W2416004425 creator A5051435890 @default.
- W2416004425 date "2002-03-29" @default.
- W2416004425 modified "2023-09-26" @default.
- W2416004425 title "Anaplastic thyroid carcinoma in ecuador: analysis of prognostic factors." @default.
- W2416004425 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11918236" @default.
- W2416004425 hasPublicationYear "2002" @default.
- W2416004425 type Work @default.
- W2416004425 sameAs 2416004425 @default.
- W2416004425 citedByCount "5" @default.
- W2416004425 countsByYear W24160044252012 @default.
- W2416004425 countsByYear W24160044252019 @default.
- W2416004425 crossrefType "journal-article" @default.
- W2416004425 hasAuthorship W2416004425A5005345650 @default.
- W2416004425 hasAuthorship W2416004425A5045726331 @default.
- W2416004425 hasAuthorship W2416004425A5051435890 @default.
- W2416004425 hasConcept C120665830 @default.
- W2416004425 hasConcept C121332964 @default.
- W2416004425 hasConcept C126322002 @default.
- W2416004425 hasConcept C126838900 @default.
- W2416004425 hasConcept C141071460 @default.
- W2416004425 hasConcept C144301174 @default.
- W2416004425 hasConcept C2776694085 @default.
- W2416004425 hasConcept C2777074255 @default.
- W2416004425 hasConcept C2777546739 @default.
- W2416004425 hasConcept C2778981773 @default.
- W2416004425 hasConcept C2779634585 @default.
- W2416004425 hasConcept C38180746 @default.
- W2416004425 hasConcept C509974204 @default.
- W2416004425 hasConcept C526584372 @default.
- W2416004425 hasConcept C61511704 @default.
- W2416004425 hasConcept C71924100 @default.
- W2416004425 hasConceptScore W2416004425C120665830 @default.
- W2416004425 hasConceptScore W2416004425C121332964 @default.
- W2416004425 hasConceptScore W2416004425C126322002 @default.
- W2416004425 hasConceptScore W2416004425C126838900 @default.
- W2416004425 hasConceptScore W2416004425C141071460 @default.
- W2416004425 hasConceptScore W2416004425C144301174 @default.
- W2416004425 hasConceptScore W2416004425C2776694085 @default.
- W2416004425 hasConceptScore W2416004425C2777074255 @default.
- W2416004425 hasConceptScore W2416004425C2777546739 @default.
- W2416004425 hasConceptScore W2416004425C2778981773 @default.
- W2416004425 hasConceptScore W2416004425C2779634585 @default.
- W2416004425 hasConceptScore W2416004425C38180746 @default.
- W2416004425 hasConceptScore W2416004425C509974204 @default.
- W2416004425 hasConceptScore W2416004425C526584372 @default.
- W2416004425 hasConceptScore W2416004425C61511704 @default.
- W2416004425 hasConceptScore W2416004425C71924100 @default.
- W2416004425 hasIssue "2" @default.
- W2416004425 hasLocation W24160044251 @default.
- W2416004425 hasOpenAccess W2416004425 @default.
- W2416004425 hasPrimaryLocation W24160044251 @default.
- W2416004425 hasRelatedWork W2014023608 @default.
- W2416004425 hasRelatedWork W2014028138 @default.
- W2416004425 hasRelatedWork W2036826410 @default.
- W2416004425 hasRelatedWork W2350114089 @default.
- W2416004425 hasRelatedWork W2379082095 @default.
- W2416004425 hasRelatedWork W2391354688 @default.
- W2416004425 hasRelatedWork W2417826953 @default.
- W2416004425 hasRelatedWork W2947300681 @default.
- W2416004425 hasRelatedWork W3164099605 @default.
- W2416004425 hasRelatedWork W4235734420 @default.
- W2416004425 hasVolume "86" @default.
- W2416004425 isParatext "false" @default.
- W2416004425 isRetracted "false" @default.
- W2416004425 magId "2416004425" @default.
- W2416004425 workType "article" @default.