Matches in SemOpenAlex for { <https://semopenalex.org/work/W2416101065> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2416101065 endingPage "206" @default.
- W2416101065 startingPage "201" @default.
- W2416101065 abstract "Introduction: Some studies indicate, that the Trp 64 /Arg 64 polymorphism of β 3 -adrenergic receptor (ADRB3) is associatedwith obesity, insulin resistance and earlier onset of type 2 diabetes mellitus.The aim of our study was evaluation of frequency of this ADRB3 polymorphism and his association with metabolic syndromeparameters and oxidative stress in postmenopausal women. Material and methods: We performed the study among 94 women, aged 50-60, selected randomly from Wroclaw citypopulation. Estimation of anthropometric parameters, densitometry (total body fat, android and gynoid deposits - usingDPX(+) Lunar, USA device) and biochemical estimations such as lipid profile, glucose, insulin, estradiol and FSH serumlevel (using commercial kits) were carried out. Oxidative stress was estimated by measurement of thiobarbituric-reactivesubstances (TBARS) serum concentration, using Yagi method, on spectrofluorimeter Perkin-Elmer LS55. Blood for analysiswas collected before, direct after and 6 h after the 30-minutes physical test using cycloergometer. ADRB3 genotyping wasperformed by PCR and minisequencing using ABI 310 sequencer (Applied Biosystems). Results: The frequency of Trp 64 /Arg 64 genotype in investigated population was 15.8%. The Arg 64 /Arg 64 genotype had onlyone woman. Women bearing Trp 64 /Arg 64 genotype showed higher mean serum level of triglycerides and lower serum levelof HDL-cholesterol in comparison to women bearing Trp 64 /Trp 64 genotype, however without statistical significance (p > 0.05)(respectively, means ± SD for triglycerides: 140.3 ± 64.1 vs. 113.9 ± 56.2 mg/dl; and for HDL-cholesterol: 60.9 ± 11.9 vs. 67.0 ± 16.9 mg/dl). Both groups did not differ in any other investigated anthropometric nor biochemic parameter. Conclusions: 1. The Trp 64 /Arg 64 polymorphism of β 3 -adrenergic receptor could be associated with lipid profile disodersobserved in metabolic syndrome in postmenopausal women, however it should be explaned basing on the study withmore included subjects. 2. The Trp 64 /Arg 64 polymorphism of β 3 -adrenergic receptor has no influence on oxidative stressintensification after standardized physical effort in postmenopausal women. (Pol J Endocrinol 2007; 58 (3): 201-206)" @default.
- W2416101065 created "2016-06-24" @default.
- W2416101065 creator A5013337799 @default.
- W2416101065 creator A5031279343 @default.
- W2416101065 creator A5034150256 @default.
- W2416101065 creator A5056530288 @default.
- W2416101065 creator A5069465086 @default.
- W2416101065 date "2007-05-01" @default.
- W2416101065 modified "2023-09-26" @default.
- W2416101065 title "[Relationship of beta(3)-adrenergic receptor polymorphism with metabolic syndrome and oxidative stress parameters in postmenopausal women]." @default.
- W2416101065 cites W125064021 @default.
- W2416101065 cites W1970934755 @default.
- W2416101065 cites W1976279454 @default.
- W2416101065 cites W1977720886 @default.
- W2416101065 cites W1993244369 @default.
- W2416101065 cites W2000262969 @default.
- W2416101065 cites W2023329039 @default.
- W2416101065 cites W2025795822 @default.
- W2416101065 cites W2029777615 @default.
- W2416101065 cites W2033568251 @default.
- W2416101065 cites W2055689111 @default.
- W2416101065 cites W2072147633 @default.
- W2416101065 cites W2091272291 @default.
- W2416101065 cites W2091917754 @default.
- W2416101065 cites W2100498235 @default.
- W2416101065 cites W2110713453 @default.
- W2416101065 cites W2136437813 @default.
- W2416101065 cites W2141599040 @default.
- W2416101065 cites W2322463216 @default.
- W2416101065 cites W2336925169 @default.
- W2416101065 cites W54786159 @default.
- W2416101065 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17940985" @default.
- W2416101065 hasPublicationYear "2007" @default.
- W2416101065 type Work @default.
- W2416101065 sameAs 2416101065 @default.
- W2416101065 citedByCount "1" @default.
- W2416101065 crossrefType "journal-article" @default.
- W2416101065 hasAuthorship W2416101065A5013337799 @default.
- W2416101065 hasAuthorship W2416101065A5031279343 @default.
- W2416101065 hasAuthorship W2416101065A5034150256 @default.
- W2416101065 hasAuthorship W2416101065A5056530288 @default.
- W2416101065 hasAuthorship W2416101065A5069465086 @default.
- W2416101065 hasConcept C104317684 @default.
- W2416101065 hasConcept C126322002 @default.
- W2416101065 hasConcept C134018914 @default.
- W2416101065 hasConcept C135763542 @default.
- W2416101065 hasConcept C2776151105 @default.
- W2416101065 hasConcept C2779306644 @default.
- W2416101065 hasConcept C2908647359 @default.
- W2416101065 hasConcept C31467283 @default.
- W2416101065 hasConcept C54355233 @default.
- W2416101065 hasConcept C555293320 @default.
- W2416101065 hasConcept C71924100 @default.
- W2416101065 hasConcept C86803240 @default.
- W2416101065 hasConcept C99454951 @default.
- W2416101065 hasConceptScore W2416101065C104317684 @default.
- W2416101065 hasConceptScore W2416101065C126322002 @default.
- W2416101065 hasConceptScore W2416101065C134018914 @default.
- W2416101065 hasConceptScore W2416101065C135763542 @default.
- W2416101065 hasConceptScore W2416101065C2776151105 @default.
- W2416101065 hasConceptScore W2416101065C2779306644 @default.
- W2416101065 hasConceptScore W2416101065C2908647359 @default.
- W2416101065 hasConceptScore W2416101065C31467283 @default.
- W2416101065 hasConceptScore W2416101065C54355233 @default.
- W2416101065 hasConceptScore W2416101065C555293320 @default.
- W2416101065 hasConceptScore W2416101065C71924100 @default.
- W2416101065 hasConceptScore W2416101065C86803240 @default.
- W2416101065 hasConceptScore W2416101065C99454951 @default.
- W2416101065 hasIssue "3" @default.
- W2416101065 hasLocation W24161010651 @default.
- W2416101065 hasLocation W24161010652 @default.
- W2416101065 hasOpenAccess W2416101065 @default.
- W2416101065 hasPrimaryLocation W24161010651 @default.
- W2416101065 hasRelatedWork W1547126286 @default.
- W2416101065 hasRelatedWork W1964965077 @default.
- W2416101065 hasRelatedWork W1990127792 @default.
- W2416101065 hasRelatedWork W2013857760 @default.
- W2416101065 hasRelatedWork W2028168246 @default.
- W2416101065 hasRelatedWork W2029269750 @default.
- W2416101065 hasRelatedWork W2042694949 @default.
- W2416101065 hasRelatedWork W2068005384 @default.
- W2416101065 hasRelatedWork W2071273970 @default.
- W2416101065 hasRelatedWork W2115994010 @default.
- W2416101065 hasRelatedWork W2118387179 @default.
- W2416101065 hasRelatedWork W2127322405 @default.
- W2416101065 hasRelatedWork W2138020946 @default.
- W2416101065 hasRelatedWork W2142444352 @default.
- W2416101065 hasRelatedWork W2149926346 @default.
- W2416101065 hasRelatedWork W2283942786 @default.
- W2416101065 hasRelatedWork W2399305434 @default.
- W2416101065 hasRelatedWork W3023360249 @default.
- W2416101065 hasRelatedWork W3023443986 @default.
- W2416101065 hasRelatedWork W2109663444 @default.
- W2416101065 hasVolume "58" @default.
- W2416101065 isParatext "false" @default.
- W2416101065 isRetracted "false" @default.
- W2416101065 magId "2416101065" @default.
- W2416101065 workType "article" @default.