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• W2416183604 abstract "The interaction of polysaccharides with proteins modulates or triggers many biological effects. In particular, heparan sulphate proteoglycans (HSPGs) have multiple regulatory interactions with growth factors, enzymes, enzyme inhibitors, and some components of the extracellular matrix. The important role played by HSPGs has motivated the synthesis and selection of HSPG mimetics for modulating the biological activity of HS-binding proteins. We present hereinafter an efficient polysaccharide microarray method that allows the screening of HS-mimetic libraries towards HS-binding growth factors, a major class of polypeptides whose inhibition or potentiation is of high medical interest." @default.
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• W2416183604 date "2011-09-28" @default.
• W2416183604 modified "2023-10-12" @default.
• W2416183604 title "Polysaccharide Microarrays: Application to the Identification of Heparan Sulphate Mimetics" @default.
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• W2416183604 doi "https://doi.org/10.1007/978-1-61779-373-8_16" @default.
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