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- W2416408979 abstract "Penimocycline is an antibiotic obtained by Mannich reaction between tetracycline and ampicilline. Separation of penimocycline from tetracyclines and other impurities has been studied by high-performance liquid chromatography. The most effective method is liquid-liquid partition on a Micropak CH column (non-polar hydrocarbon bonded on porous silica microparticles) and gradient elution with water-methanol, 0.02 M phosphate buffer (pH 7.6) and 1 mM EDTA. Some results on hydrolysis of penimocycline are given." @default.
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- W2416408979 date "1976-09-01" @default.
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- W2416408979 title "Étude de la pénimocycline par chromatographie en phase liquide à haute performance" @default.
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- W2416408979 doi "https://doi.org/10.1016/s0021-9673(00)89750-2" @default.
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