Matches in SemOpenAlex for { <https://semopenalex.org/work/W2416471330> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2416471330 endingPage "43" @default.
- W2416471330 startingPage "937" @default.
- W2416471330 abstract "Histopathological and immunohistochemical studies were carried out on D-galactosamine (GalNAc)-induced acute hepatitis in rats of the JCI: Wistar TgN (ARGHGEN) 1 Nts strain (Mini rats), in which expression of the growth hormone gene is suppressed by an antisense transgene. Hepatitis characterized by hepatocellular acidophilic necrosis with inflammatory cell infiltration was most prominent at 2 days after GalNAc (1000 mg/kg)-injection, when proliferation of Ito cells and deposition of fibronectin and laminin were found along the sinusoidal linings. At 72 hours after GalNAc-injection, Ito cell proliferation with deposition of laminin and fibronectin became more prominent, and marked proliferation of small epithelial cells was observed in the periportal area. At 7 days after GalNAc-injection, quite a number of alpha-smooth muscle actin-positive Ito cells, surrounded by abundant fibronectin, laminin and type IV collagen, were still observed in close juxtaposition to rapidly proliferating small epithelial cells. The small epithelial cells were found to be positive for both alpha-fetoprotein and cytokeratin 7 and were therefore considered to be so-called oval cells. The results suggest that there may be some relation between oval cell proliferation, Ito cell activation and extracellular matrix accumulation in GalNAc-induced acute hepatitis in Mini rats." @default.
- W2416471330 created "2016-06-24" @default.
- W2416471330 creator A5034417976 @default.
- W2416471330 creator A5038378558 @default.
- W2416471330 creator A5073150594 @default.
- W2416471330 creator A5086535576 @default.
- W2416471330 date "1997-10-01" @default.
- W2416471330 modified "2023-10-02" @default.
- W2416471330 title "Prolonged oval cell proliferation with Ito cell activation and extracellular matrix accumulation in galactosamine-induced acute hepatitis in mini rats." @default.
- W2416471330 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9302554" @default.
- W2416471330 hasPublicationYear "1997" @default.
- W2416471330 type Work @default.
- W2416471330 sameAs 2416471330 @default.
- W2416471330 citedByCount "9" @default.
- W2416471330 crossrefType "journal-article" @default.
- W2416471330 hasAuthorship W2416471330A5034417976 @default.
- W2416471330 hasAuthorship W2416471330A5038378558 @default.
- W2416471330 hasAuthorship W2416471330A5073150594 @default.
- W2416471330 hasAuthorship W2416471330A5086535576 @default.
- W2416471330 hasConcept C126322002 @default.
- W2416471330 hasConcept C142724271 @default.
- W2416471330 hasConcept C1491633281 @default.
- W2416471330 hasConcept C153911025 @default.
- W2416471330 hasConcept C185592680 @default.
- W2416471330 hasConcept C189165786 @default.
- W2416471330 hasConcept C203014093 @default.
- W2416471330 hasConcept C204232928 @default.
- W2416471330 hasConcept C2779012181 @default.
- W2416471330 hasConcept C2779814568 @default.
- W2416471330 hasConcept C2992672570 @default.
- W2416471330 hasConcept C34688535 @default.
- W2416471330 hasConcept C55493867 @default.
- W2416471330 hasConcept C62112901 @default.
- W2416471330 hasConcept C71924100 @default.
- W2416471330 hasConcept C86492073 @default.
- W2416471330 hasConcept C86803240 @default.
- W2416471330 hasConcept C95444343 @default.
- W2416471330 hasConceptScore W2416471330C126322002 @default.
- W2416471330 hasConceptScore W2416471330C142724271 @default.
- W2416471330 hasConceptScore W2416471330C1491633281 @default.
- W2416471330 hasConceptScore W2416471330C153911025 @default.
- W2416471330 hasConceptScore W2416471330C185592680 @default.
- W2416471330 hasConceptScore W2416471330C189165786 @default.
- W2416471330 hasConceptScore W2416471330C203014093 @default.
- W2416471330 hasConceptScore W2416471330C204232928 @default.
- W2416471330 hasConceptScore W2416471330C2779012181 @default.
- W2416471330 hasConceptScore W2416471330C2779814568 @default.
- W2416471330 hasConceptScore W2416471330C2992672570 @default.
- W2416471330 hasConceptScore W2416471330C34688535 @default.
- W2416471330 hasConceptScore W2416471330C55493867 @default.
- W2416471330 hasConceptScore W2416471330C62112901 @default.
- W2416471330 hasConceptScore W2416471330C71924100 @default.
- W2416471330 hasConceptScore W2416471330C86492073 @default.
- W2416471330 hasConceptScore W2416471330C86803240 @default.
- W2416471330 hasConceptScore W2416471330C95444343 @default.
- W2416471330 hasIssue "4" @default.
- W2416471330 hasLocation W24164713301 @default.
- W2416471330 hasOpenAccess W2416471330 @default.
- W2416471330 hasPrimaryLocation W24164713301 @default.
- W2416471330 hasRelatedWork W1572272708 @default.
- W2416471330 hasRelatedWork W1988289599 @default.
- W2416471330 hasRelatedWork W1995440302 @default.
- W2416471330 hasRelatedWork W2061352421 @default.
- W2416471330 hasRelatedWork W2071113717 @default.
- W2416471330 hasRelatedWork W2077457354 @default.
- W2416471330 hasRelatedWork W2093479340 @default.
- W2416471330 hasRelatedWork W2101325041 @default.
- W2416471330 hasRelatedWork W2110999655 @default.
- W2416471330 hasRelatedWork W2416471330 @default.
- W2416471330 hasVolume "12" @default.
- W2416471330 isParatext "false" @default.
- W2416471330 isRetracted "false" @default.
- W2416471330 magId "2416471330" @default.
- W2416471330 workType "article" @default.