Matches in SemOpenAlex for { <https://semopenalex.org/work/W2416498869> ?p ?o ?g. }
- W2416498869 endingPage "251" @default.
- W2416498869 startingPage "239" @default.
- W2416498869 abstract "Reactive oxygen species (ROS) play an important role in signal transduction and metabolism. Over-produced ROS in cells or tissues, however, often leads to oxidation stress that has implications in a series of diseases including cancer, aging, atherosclerosis and inflammation. Driven by the need for on-demand drug delivery and fuelled by recent development of ROS-responsive materials and nanomedicine, responsive drug delivery systems (DDSs) have gained increasing research interest. ROS-responsive DDS is designed to release therapeutic agents only in targets of interest that produce excessive ROS, which may lead to both enhanced therapeutic efficiency and reduced side effects. Multiple-stimuli responsive DDSs that are also sensitive to other stimuli can further enhance controlled drug release in sites where multiple stimuli coexist. Beyond drug delivery, multifunctional DDSs have great potential in achieving simultaneous imaging, combinatorial therapy and targeting ability by introducing multifunctional elements such as signal reporter, targeting elements and photosensitizer. This review will summarize the latest development of ROS-responsive DDSs and discuss their design principle and biomedical applications." @default.
- W2416498869 created "2016-06-24" @default.
- W2416498869 creator A5015439597 @default.
- W2416498869 creator A5051463252 @default.
- W2416498869 date "2016-07-05" @default.
- W2416498869 modified "2023-10-17" @default.
- W2416498869 title "ROS‐responsive drug delivery systems" @default.
- W2416498869 cites W1917939198 @default.
- W2416498869 cites W1965675819 @default.
- W2416498869 cites W1967290375 @default.
- W2416498869 cites W1968237854 @default.
- W2416498869 cites W1977508132 @default.
- W2416498869 cites W1978609085 @default.
- W2416498869 cites W1989745873 @default.
- W2416498869 cites W1993250284 @default.
- W2416498869 cites W1994942442 @default.
- W2416498869 cites W2004461657 @default.
- W2416498869 cites W2006595429 @default.
- W2416498869 cites W2008294808 @default.
- W2416498869 cites W2027008188 @default.
- W2416498869 cites W2038720439 @default.
- W2416498869 cites W2039140384 @default.
- W2416498869 cites W2043304304 @default.
- W2416498869 cites W2048194629 @default.
- W2416498869 cites W2062786004 @default.
- W2416498869 cites W2064769568 @default.
- W2416498869 cites W2066942909 @default.
- W2416498869 cites W2067492397 @default.
- W2416498869 cites W2069119383 @default.
- W2416498869 cites W2072398658 @default.
- W2416498869 cites W2082490680 @default.
- W2416498869 cites W2086019263 @default.
- W2416498869 cites W2090775890 @default.
- W2416498869 cites W2090900051 @default.
- W2416498869 cites W2091716603 @default.
- W2416498869 cites W2092685208 @default.
- W2416498869 cites W2093460728 @default.
- W2416498869 cites W2102472842 @default.
- W2416498869 cites W2107863636 @default.
- W2416498869 cites W2117289416 @default.
- W2416498869 cites W2123617256 @default.
- W2416498869 cites W2129778797 @default.
- W2416498869 cites W2130166533 @default.
- W2416498869 cites W2130495733 @default.
- W2416498869 cites W2132118277 @default.
- W2416498869 cites W2132693984 @default.
- W2416498869 cites W2133452519 @default.
- W2416498869 cites W2137485942 @default.
- W2416498869 cites W2142201053 @default.
- W2416498869 cites W2145381930 @default.
- W2416498869 cites W2152429732 @default.
- W2416498869 cites W2156177984 @default.
- W2416498869 cites W2157459474 @default.
- W2416498869 cites W2168203225 @default.
- W2416498869 cites W2174394355 @default.
- W2416498869 cites W2176124759 @default.
- W2416498869 cites W2179022277 @default.
- W2416498869 cites W2196654243 @default.
- W2416498869 cites W2215236428 @default.
- W2416498869 cites W2223635015 @default.
- W2416498869 cites W2240820333 @default.
- W2416498869 cites W2294629481 @default.
- W2416498869 cites W2316362899 @default.
- W2416498869 cites W2320599846 @default.
- W2416498869 cites W2323137482 @default.
- W2416498869 cites W2325312944 @default.
- W2416498869 cites W2327911798 @default.
- W2416498869 cites W2328509024 @default.
- W2416498869 cites W2329599594 @default.
- W2416498869 cites W2419230544 @default.
- W2416498869 cites W32337113 @default.
- W2416498869 cites W4241175784 @default.
- W2416498869 cites W4242509007 @default.
- W2416498869 cites W4245591226 @default.
- W2416498869 doi "https://doi.org/10.1002/btm2.10014" @default.
- W2416498869 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5689534" @default.
- W2416498869 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29313015" @default.
- W2416498869 hasPublicationYear "2016" @default.
- W2416498869 type Work @default.
- W2416498869 sameAs 2416498869 @default.
- W2416498869 citedByCount "125" @default.
- W2416498869 countsByYear W24164988692016 @default.
- W2416498869 countsByYear W24164988692017 @default.
- W2416498869 countsByYear W24164988692018 @default.
- W2416498869 countsByYear W24164988692019 @default.
- W2416498869 countsByYear W24164988692020 @default.
- W2416498869 countsByYear W24164988692021 @default.
- W2416498869 countsByYear W24164988692022 @default.
- W2416498869 countsByYear W24164988692023 @default.
- W2416498869 crossrefType "journal-article" @default.
- W2416498869 hasAuthorship W2416498869A5015439597 @default.
- W2416498869 hasAuthorship W2416498869A5051463252 @default.
- W2416498869 hasBestOaLocation W24164988691 @default.
- W2416498869 hasConcept C15083742 @default.
- W2416498869 hasConcept C155672457 @default.
- W2416498869 hasConcept C171250308 @default.
- W2416498869 hasConcept C178790620 @default.
- W2416498869 hasConcept C185592680 @default.