FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2416537745> ?p ?o ?g. }

• W2416537745 endingPage "40" @default.
• W2416537745 startingPage "33" @default.
• W2416537745 abstract "Taxane is one of the most effective drugs used for advanced metastatic breast cancer treatment. Conventional 3-weekly regimens are widely used with significant treatment related toxicity. Recently, weekly schedules of taxane were reported to be effective and well tolerated in this patient group. We retrospectively evaluated the efficacy of weekly paclitaxel in women with metastatic breast cancer.Between December 1999 and June 2004, a total of twenty-three patients with histologically confirmed and measurable pretreated metastatic breast cancer were included. The median age was 55 years (range 33 to approximately 73). Their performance status was ECOG < or = 2. All patients had received at least one regimen for metastatic disease. Paclitaxel 80 mg/m2 was administered weekly for 3 weeks per 4-week cycle. WHO response criteria was used as the reference to evaluate the response to treatment.The response and survival of all patients were assessed. All had prior anthracycline-based chemotherapy; 14 patients (61%) had at least 3 different chemotherapy lines before this regimen. Twenty patients (87%) had at least 2 metastatic sites and 18 (78.3%) had visceral metastasis. The overall response rate was 21.7% with no complete response, while 43.5% had stable disease. The median time to progression was 121 days. Four patients (17.4%) were treated with a trastuzumab-paclitaxel combination, and 2 of them responded. The therapy was well tolerated and there were no grade III/IV toxicities observed. Only 1 patient (4.35%) dropped out because of heart failure.Weekly paclitaxel was well tolerated and the response rate was comparable to that previously reported in heavily pretreated patients with metastatic breast cancer. Weekly paclitaxel in combination with other agents is worthy of further investigation." @default.
• W2416537745 created "2016-06-24" @default.
• W2416537745 creator A5030330847 @default.
• W2416537745 creator A5050473175 @default.
• W2416537745 creator A5089770713 @default.
• W2416537745 date "2007-05-05" @default.
• W2416537745 modified "2023-09-23" @default.
• W2416537745 title "Weekly paclitaxel in women with heavily pretreated metastatic breast cancer: a retrospective analysis of cases treated at the Chang Gung Memorial Hospital." @default.
• W2416537745 cites W1616592835 @default.
• W2416537745 cites W1830813972 @default.
• W2416537745 cites W1880426265 @default.
• W2416537745 cites W1888433797 @default.
• W2416537745 cites W1938913042 @default.
• W2416537745 cites W1946759281 @default.
• W2416537745 cites W1946819517 @default.
• W2416537745 cites W1978291661 @default.
• W2416537745 cites W1980923728 @default.
• W2416537745 cites W2038058305 @default.
• W2416537745 cites W2063667079 @default.
• W2416537745 cites W2092981846 @default.
• W2416537745 cites W2110183632 @default.
• W2416537745 cites W2113043752 @default.
• W2416537745 cites W2114974083 @default.
• W2416537745 cites W2133243551 @default.
• W2416537745 cites W2135459504 @default.
• W2416537745 cites W2142760959 @default.
• W2416537745 cites W2167211185 @default.
• W2416537745 cites W2178225042 @default.
• W2416537745 cites W2303074060 @default.
• W2416537745 cites W2315931167 @default.
• W2416537745 cites W2326176922 @default.
• W2416537745 cites W2414172943 @default.
• W2416537745 cites W2418209683 @default.
• W2416537745 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17477027" @default.
• W2416537745 hasPublicationYear "2007" @default.
• W2416537745 type Work @default.
• W2416537745 sameAs 2416537745 @default.
• W2416537745 citedByCount "1" @default.
• W2416537745 crossrefType "journal-article" @default.
• W2416537745 hasAuthorship W2416537745A5030330847 @default.
• W2416537745 hasAuthorship W2416537745A5050473175 @default.
• W2416537745 hasAuthorship W2416537745A5089770713 @default.
• W2416537745 hasConcept C121608353 @default.
• W2416537745 hasConcept C126322002 @default.
• W2416537745 hasConcept C141071460 @default.
• W2416537745 hasConcept C143998085 @default.
• W2416537745 hasConcept C2775930923 @default.
• W2416537745 hasConcept C2776694085 @default.
• W2416537745 hasConcept C2776802502 @default.
• W2416537745 hasConcept C2777292972 @default.
• W2416537745 hasConcept C2777511904 @default.
• W2416537745 hasConcept C2779786085 @default.
• W2416537745 hasConcept C2781413609 @default.
• W2416537745 hasConcept C530470458 @default.
• W2416537745 hasConcept C71924100 @default.
• W2416537745 hasConceptScore W2416537745C121608353 @default.
• W2416537745 hasConceptScore W2416537745C126322002 @default.
• W2416537745 hasConceptScore W2416537745C141071460 @default.
• W2416537745 hasConceptScore W2416537745C143998085 @default.
• W2416537745 hasConceptScore W2416537745C2775930923 @default.
• W2416537745 hasConceptScore W2416537745C2776694085 @default.
• W2416537745 hasConceptScore W2416537745C2776802502 @default.
• W2416537745 hasConceptScore W2416537745C2777292972 @default.
• W2416537745 hasConceptScore W2416537745C2777511904 @default.
• W2416537745 hasConceptScore W2416537745C2779786085 @default.
• W2416537745 hasConceptScore W2416537745C2781413609 @default.
• W2416537745 hasConceptScore W2416537745C530470458 @default.
• W2416537745 hasConceptScore W2416537745C71924100 @default.
• W2416537745 hasIssue "1" @default.
• W2416537745 hasLocation W24165377451 @default.
• W2416537745 hasOpenAccess W2416537745 @default.
• W2416537745 hasPrimaryLocation W24165377451 @default.
• W2416537745 hasRelatedWork W1966468630 @default.
• W2416537745 hasRelatedWork W2004505747 @default.
• W2416537745 hasRelatedWork W2050038108 @default.
• W2416537745 hasRelatedWork W2112721704 @default.
• W2416537745 hasRelatedWork W2227329646 @default.
• W2416537745 hasRelatedWork W2401765432 @default.
• W2416537745 hasRelatedWork W2432872277 @default.
• W2416537745 hasRelatedWork W2980453143 @default.
• W2416537745 hasRelatedWork W3041235120 @default.
• W2416537745 hasRelatedWork W1888422595 @default.
• W2416537745 hasVolume "30" @default.
• W2416537745 isParatext "false" @default.
• W2416537745 isRetracted "false" @default.
• W2416537745 magId "2416537745" @default.
• W2416537745 workType "article" @default.