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- W2416615255 abstract "The antiarrhythmic properties of the Na+/H(+)-exchanger inhibitor zoniporide have been studied in experiments on rats. On the model of 45-min myocardial ischemia followed by 45-min reperfusion, the drug produced a significant (two-fold) decrease in the intensity of post-reperfusion arrhythmias (p < or = 0.05). On the model of 7-min ischemia followed by 5-min reperfusion, zoniporide prevented the development of ventricular fibrillation in 71.43% of cases as compared to control (p < or = 0.05). The drug also increased the threshold of electrical fibrillation by 69.23% and reduced the time to recovery of the heart rhythm by 37.85%." @default.
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- W2416615255 date "2014-01-01" @default.
- W2416615255 modified "2023-09-23" @default.
- W2416615255 title "[Experimental study of the antiarrhythmic properties of zoniporide]." @default.
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