Matches in SemOpenAlex for { <https://semopenalex.org/work/W2416785689> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W2416785689 endingPage "9" @default.
- W2416785689 startingPage "87" @default.
- W2416785689 abstract "On an experimental model created from semiaerobically cultivated yeast cells of Caccharomyces cerevisiae (RIMB-75) the authors tested the effect of antimalarics used or tested for treatment of symptomatic liver porphyria. Chloroquine and pyrimethamine inhibited the synthesis of porphyrins, whereby pyrimethamine was more effective. Chloroquine released moreover intracellular porphyrins, contrary to pyrimethamine, which caused their intracellular cumulation. An equimolar combination of the two preparations preserved the inhibitory action of pyrimethamine, and the intracellular porphyrin content was reduced. Based on experimental results the suggested combination of chloroquine and pyrimethamine was successfully tested in clinical work." @default.
- W2416785689 created "2016-06-24" @default.
- W2416785689 creator A5029074725 @default.
- W2416785689 creator A5049997457 @default.
- W2416785689 creator A5067813961 @default.
- W2416785689 creator A5089825605 @default.
- W2416785689 date "1989-01-13" @default.
- W2416785689 modified "2023-10-18" @default.
- W2416785689 title "[Experimental study of the action of antimalarial agents with respect to therapy in porphyria. Combined effect of chloroquine and pyrimethamine]." @default.
- W2416785689 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2655915" @default.
- W2416785689 hasPublicationYear "1989" @default.
- W2416785689 type Work @default.
- W2416785689 sameAs 2416785689 @default.
- W2416785689 citedByCount "0" @default.
- W2416785689 crossrefType "journal-article" @default.
- W2416785689 hasAuthorship W2416785689A5029074725 @default.
- W2416785689 hasAuthorship W2416785689A5049997457 @default.
- W2416785689 hasAuthorship W2416785689A5067813961 @default.
- W2416785689 hasAuthorship W2416785689A5089825605 @default.
- W2416785689 hasConcept C185592680 @default.
- W2416785689 hasConcept C202751555 @default.
- W2416785689 hasConcept C203014093 @default.
- W2416785689 hasConcept C2776120743 @default.
- W2416785689 hasConcept C2777035104 @default.
- W2416785689 hasConcept C2777425658 @default.
- W2416785689 hasConcept C2778048844 @default.
- W2416785689 hasConcept C55493867 @default.
- W2416785689 hasConcept C71924100 @default.
- W2416785689 hasConcept C79879829 @default.
- W2416785689 hasConcept C98274493 @default.
- W2416785689 hasConceptScore W2416785689C185592680 @default.
- W2416785689 hasConceptScore W2416785689C202751555 @default.
- W2416785689 hasConceptScore W2416785689C203014093 @default.
- W2416785689 hasConceptScore W2416785689C2776120743 @default.
- W2416785689 hasConceptScore W2416785689C2777035104 @default.
- W2416785689 hasConceptScore W2416785689C2777425658 @default.
- W2416785689 hasConceptScore W2416785689C2778048844 @default.
- W2416785689 hasConceptScore W2416785689C55493867 @default.
- W2416785689 hasConceptScore W2416785689C71924100 @default.
- W2416785689 hasConceptScore W2416785689C79879829 @default.
- W2416785689 hasConceptScore W2416785689C98274493 @default.
- W2416785689 hasIssue "3" @default.
- W2416785689 hasLocation W24167856891 @default.
- W2416785689 hasOpenAccess W2416785689 @default.
- W2416785689 hasPrimaryLocation W24167856891 @default.
- W2416785689 hasRelatedWork W1438084400 @default.
- W2416785689 hasRelatedWork W1970702698 @default.
- W2416785689 hasRelatedWork W1983055567 @default.
- W2416785689 hasRelatedWork W2014082224 @default.
- W2416785689 hasRelatedWork W2038495933 @default.
- W2416785689 hasRelatedWork W2132564799 @default.
- W2416785689 hasRelatedWork W2332345789 @default.
- W2416785689 hasRelatedWork W2397708872 @default.
- W2416785689 hasRelatedWork W2651718056 @default.
- W2416785689 hasRelatedWork W2899084033 @default.
- W2416785689 hasVolume "128" @default.
- W2416785689 isParatext "false" @default.
- W2416785689 isRetracted "false" @default.
- W2416785689 magId "2416785689" @default.
- W2416785689 workType "article" @default.