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- W2416914285 abstract "BACKGROUND Whipple's is a rare infectious disease. This review describes the clinical picture, diagnostic aspects and treatment options. MATERIAL AND METHODS Based on a clinical case, a literature study was performed by searching PubMed (unlimited) with the words whipples disease combined with TROPHERYMA WHIPPELII: (118 hits) and TROPHERYMA WHIPPLEI: (65 hits). Titles and abstracts were used to identify other relevant articles. RESULTS AND INTERPRETATION Whipple's may affect several organ systems and thus causes a wide range of symptoms. The most common ones are weight loss, abdominal pain, diarrhoea and arthralgia. The diagnosis is based on PAS-POSITIVE MATERIAL: in duodenal biopsies and identification of gene fragments from the bacterium TROPHERYMA WHIPPLEI:. Presence of the bacterium may be confirmed by sensitive polymerase chain reaction assays. Left without treatment the may be lethal. Proper antibiotic treatment is imperative to heal the disease." @default.
- W2416914285 created "2016-06-24" @default.
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- W2416914285 date "2008-06-12" @default.
- W2416914285 modified "2023-09-25" @default.
- W2416914285 title "[Whipple's disease]." @default.
- W2416914285 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18552903" @default.
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