Matches in SemOpenAlex for { <https://semopenalex.org/work/W2417365762> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2417365762 endingPage "L685" @default.
- W2417365762 startingPage "L679" @default.
- W2417365762 abstract "To investigate the role of iron, ascorbate, and fructose on copper depletion and the effect of copper depletion on neonatal lung collagen, elastin, and surfactant, female rabbits were fed a control diet [10 parts per million (ppm) copper], a basal marginal copper diet (1.5 ppm), or a basal diet containing a high concentration of iron (1,750 ppm), ascorbic acid (1%, wt/wt), or fructose (20% of carbohydrates, wt/wt) or a combination of iron, ascorbic acid, and fructose throughout gestation. Whereas 10% of neonates in the control group died in the first 24 h, 27-67% of the offspring of rabbits fed the marginal copper diet died. Birth weight was also lower for the pups of the females fed the marginal copper diets. Lungs of neonates born to females fed iron or ascorbate and marginal copper diets had low levels of copper, high proportions of acid-extractable, high-molecular-weight collagen, and low lysyl-oxidase activities, consistent with incomplete maturation of collagen. The bronchoalveolar lavage fluids of newborns whose mothers were fed marginal copper diets alone or in combination with iron and/or ascorbate had lower levels of total surfactant phospholipids than the fluids from lungs of control newborns. The lower surfactant phospholipid content of these groups could be attributed mainly to lower phosphatidylcholine and, in particular, dipalmitoylphosphatidylcholine levels. These results suggest that high maternal intakes of iron, ascorbate, or their combination in pregnancy deplete biologically available copper, which in turn induces neonatal lung abnormalities." @default.
- W2417365762 created "2016-06-24" @default.
- W2417365762 creator A5023371818 @default.
- W2417365762 creator A5050023789 @default.
- W2417365762 creator A5067615609 @default.
- W2417365762 creator A5084163979 @default.
- W2417365762 date "1994-12-01" @default.
- W2417365762 modified "2023-09-26" @default.
- W2417365762 title "Perinatal hypocuprosis affects synthesis and composition of neonatal lung collagen, elastin, and surfactant" @default.
- W2417365762 doi "https://doi.org/10.1152/ajplung.1994.267.6.l679" @default.
- W2417365762 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7810672" @default.
- W2417365762 hasPublicationYear "1994" @default.
- W2417365762 type Work @default.
- W2417365762 sameAs 2417365762 @default.
- W2417365762 citedByCount "5" @default.
- W2417365762 countsByYear W24173657622012 @default.
- W2417365762 countsByYear W24173657622014 @default.
- W2417365762 crossrefType "journal-article" @default.
- W2417365762 hasAuthorship W2417365762A5023371818 @default.
- W2417365762 hasAuthorship W2417365762A5050023789 @default.
- W2417365762 hasAuthorship W2417365762A5067615609 @default.
- W2417365762 hasAuthorship W2417365762A5084163979 @default.
- W2417365762 hasConcept C112672928 @default.
- W2417365762 hasConcept C126322002 @default.
- W2417365762 hasConcept C134018914 @default.
- W2417365762 hasConcept C178790620 @default.
- W2417365762 hasConcept C185592680 @default.
- W2417365762 hasConcept C189165786 @default.
- W2417365762 hasConcept C193143273 @default.
- W2417365762 hasConcept C2776330855 @default.
- W2417365762 hasConcept C2777714996 @default.
- W2417365762 hasConcept C2778918659 @default.
- W2417365762 hasConcept C2779234561 @default.
- W2417365762 hasConcept C2779869378 @default.
- W2417365762 hasConcept C2986274086 @default.
- W2417365762 hasConcept C31903555 @default.
- W2417365762 hasConcept C41625074 @default.
- W2417365762 hasConcept C54355233 @default.
- W2417365762 hasConcept C544778455 @default.
- W2417365762 hasConcept C55493867 @default.
- W2417365762 hasConcept C58226133 @default.
- W2417365762 hasConcept C71924100 @default.
- W2417365762 hasConcept C86803240 @default.
- W2417365762 hasConceptScore W2417365762C112672928 @default.
- W2417365762 hasConceptScore W2417365762C126322002 @default.
- W2417365762 hasConceptScore W2417365762C134018914 @default.
- W2417365762 hasConceptScore W2417365762C178790620 @default.
- W2417365762 hasConceptScore W2417365762C185592680 @default.
- W2417365762 hasConceptScore W2417365762C189165786 @default.
- W2417365762 hasConceptScore W2417365762C193143273 @default.
- W2417365762 hasConceptScore W2417365762C2776330855 @default.
- W2417365762 hasConceptScore W2417365762C2777714996 @default.
- W2417365762 hasConceptScore W2417365762C2778918659 @default.
- W2417365762 hasConceptScore W2417365762C2779234561 @default.
- W2417365762 hasConceptScore W2417365762C2779869378 @default.
- W2417365762 hasConceptScore W2417365762C2986274086 @default.
- W2417365762 hasConceptScore W2417365762C31903555 @default.
- W2417365762 hasConceptScore W2417365762C41625074 @default.
- W2417365762 hasConceptScore W2417365762C54355233 @default.
- W2417365762 hasConceptScore W2417365762C544778455 @default.
- W2417365762 hasConceptScore W2417365762C55493867 @default.
- W2417365762 hasConceptScore W2417365762C58226133 @default.
- W2417365762 hasConceptScore W2417365762C71924100 @default.
- W2417365762 hasConceptScore W2417365762C86803240 @default.
- W2417365762 hasIssue "6" @default.
- W2417365762 hasLocation W24173657621 @default.
- W2417365762 hasLocation W24173657622 @default.
- W2417365762 hasOpenAccess W2417365762 @default.
- W2417365762 hasPrimaryLocation W24173657621 @default.
- W2417365762 hasRelatedWork W194382793 @default.
- W2417365762 hasRelatedWork W2060911084 @default.
- W2417365762 hasRelatedWork W2070364452 @default.
- W2417365762 hasRelatedWork W2089155826 @default.
- W2417365762 hasRelatedWork W2130897800 @default.
- W2417365762 hasRelatedWork W2318999889 @default.
- W2417365762 hasRelatedWork W2404895785 @default.
- W2417365762 hasRelatedWork W2412693773 @default.
- W2417365762 hasRelatedWork W2417365762 @default.
- W2417365762 hasRelatedWork W62271194 @default.
- W2417365762 hasVolume "267" @default.
- W2417365762 isParatext "false" @default.
- W2417365762 isRetracted "false" @default.
- W2417365762 magId "2417365762" @default.
- W2417365762 workType "article" @default.