Matches in SemOpenAlex for { <https://semopenalex.org/work/W2417366906> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2417366906 endingPage "81" @default.
- W2417366906 startingPage "73" @default.
- W2417366906 abstract "The role of adenosine on the regulation of mitochondrial function has been studied. In order to evaluate this the following experiments were done in isolated rat cardiomyocites and mitochondria using polarographic techniques. Cardiomyocyte oxygen consumption (MVO2) and mitochondrial respiratory function (State 3 and State 4, respiratory control index, and ADP/O ratio) were evaluated after exposure to adenosine. Cardiomyocyte MVO2 was significantly lower in cells previously exposed to adenosine (10 microM, 15 min or 30 min cell incubation) than in cells not exposed to adenosine (control). Addition of dipyridamole (10 microM) or 8-(p-Sulfophenyl) theophylline (50 microM) to cardiomyocytes before adenosine incubation prevented the adenosine-induced changes in MVO2. Mitochondria obtained from isolated perfused beating heart previously perfused with adenosine (10 microM, 30 min heart perfusion) also resulted in significant increases in ADP/O and respiratory control index compared to matching control. Mitochondria isolated from cardiomyocytes previously exposed to adenosine (10 microM, 15 min or 30 min cell incubation) resulted in a significant increase in mitochondrial ADP/O ratio compared to control. Adenosine-induced decrease in cardiomyocyte MVO2 may be related to an increase in efficiency of mitochondrial oxidative phosphorylation, and more economical use of oxygen, which is necessary for survival under ischemic stress." @default.
- W2417366906 created "2016-06-24" @default.
- W2417366906 creator A5050164299 @default.
- W2417366906 creator A5059846776 @default.
- W2417366906 creator A5064814540 @default.
- W2417366906 creator A5082999920 @default.
- W2417366906 date "1998-12-16" @default.
- W2417366906 modified "2023-09-23" @default.
- W2417366906 title "Adenosine improves cardiomyocyte respiratory efficiency." @default.
- W2417366906 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9848184" @default.
- W2417366906 hasPublicationYear "1998" @default.
- W2417366906 type Work @default.
- W2417366906 sameAs 2417366906 @default.
- W2417366906 citedByCount "0" @default.
- W2417366906 crossrefType "journal-article" @default.
- W2417366906 hasAuthorship W2417366906A5050164299 @default.
- W2417366906 hasAuthorship W2417366906A5059846776 @default.
- W2417366906 hasAuthorship W2417366906A5064814540 @default.
- W2417366906 hasAuthorship W2417366906A5082999920 @default.
- W2417366906 hasConcept C105702510 @default.
- W2417366906 hasConcept C126322002 @default.
- W2417366906 hasConcept C134018914 @default.
- W2417366906 hasConcept C146957229 @default.
- W2417366906 hasConcept C182215343 @default.
- W2417366906 hasConcept C185592680 @default.
- W2417366906 hasConcept C25642318 @default.
- W2417366906 hasConcept C2776991684 @default.
- W2417366906 hasConcept C28859421 @default.
- W2417366906 hasConcept C534529494 @default.
- W2417366906 hasConcept C55493867 @default.
- W2417366906 hasConcept C57600042 @default.
- W2417366906 hasConcept C71924100 @default.
- W2417366906 hasConcept C86803240 @default.
- W2417366906 hasConceptScore W2417366906C105702510 @default.
- W2417366906 hasConceptScore W2417366906C126322002 @default.
- W2417366906 hasConceptScore W2417366906C134018914 @default.
- W2417366906 hasConceptScore W2417366906C146957229 @default.
- W2417366906 hasConceptScore W2417366906C182215343 @default.
- W2417366906 hasConceptScore W2417366906C185592680 @default.
- W2417366906 hasConceptScore W2417366906C25642318 @default.
- W2417366906 hasConceptScore W2417366906C2776991684 @default.
- W2417366906 hasConceptScore W2417366906C28859421 @default.
- W2417366906 hasConceptScore W2417366906C534529494 @default.
- W2417366906 hasConceptScore W2417366906C55493867 @default.
- W2417366906 hasConceptScore W2417366906C57600042 @default.
- W2417366906 hasConceptScore W2417366906C71924100 @default.
- W2417366906 hasConceptScore W2417366906C86803240 @default.
- W2417366906 hasIssue "3" @default.
- W2417366906 hasLocation W24173669061 @default.
- W2417366906 hasOpenAccess W2417366906 @default.
- W2417366906 hasPrimaryLocation W24173669061 @default.
- W2417366906 hasRelatedWork W1534219729 @default.
- W2417366906 hasRelatedWork W2001671581 @default.
- W2417366906 hasRelatedWork W2028795934 @default.
- W2417366906 hasRelatedWork W2062125915 @default.
- W2417366906 hasRelatedWork W2143051876 @default.
- W2417366906 hasRelatedWork W2394837403 @default.
- W2417366906 hasRelatedWork W2419388115 @default.
- W2417366906 hasRelatedWork W2420776247 @default.
- W2417366906 hasRelatedWork W2424658077 @default.
- W2417366906 hasRelatedWork W2438312634 @default.
- W2417366906 hasVolume "70" @default.
- W2417366906 isParatext "false" @default.
- W2417366906 isRetracted "false" @default.
- W2417366906 magId "2417366906" @default.
- W2417366906 workType "article" @default.