Matches in SemOpenAlex for { <https://semopenalex.org/work/W2417470619> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2417470619 endingPage "621" @default.
- W2417470619 startingPage "617" @default.
- W2417470619 abstract "The importance of some glutathione metabolic pathways was examined in two highly dedifferentiated hepatomas, Yoshida AH-130 and Morris 3924 A hepatomas, and in normal liver in relation to their role against oxidative stress. The cytosol prepared from Yoshida hepatoma cells decreased the peroxidation rate in normal liver microsomes and mitochondria, but this antioxidant property was not displayed by Morris hepatoma. Glutathione peroxidase and glutathione-S-transferases activities were extremely low in both hepatomas; glutathione reductase activity values were about half the normal liver values. The large decrease in glutathione peroxidase and glutathione-S-transferases suggests that in these two tumors only small amounts of GSH can be used in reduction or conjugation reactions, such as the reduction of hydrogen peroxide and lipid hydroperoxides or the conjugation of GSH with the end products of lipoperoxidation, aldehydes or ketones. The hypothesis of a more efficient GSSG reduction in hepatomas, due to the low glutathione peroxidase/glutathione reductase activity ratio, is also discussed. The described changes in glutathione related enzymes do not seem to have any correlation with the protective effect against the lipoperoxidative processes displayed by some tumors since these enzymatic activities were similar in both hepatomas whereas only Yoshida hepatoma showed antioxidant properties." @default.
- W2417470619 created "2016-06-24" @default.
- W2417470619 creator A5032704680 @default.
- W2417470619 creator A5036064889 @default.
- W2417470619 date "1988-12-01" @default.
- W2417470619 modified "2023-10-18" @default.
- W2417470619 title "Analysis of Glutathione-Dependent Enzyme Activities in two Different Rat Hepatomas and in Normal Liver in Relation to their Role in Resistance to Oxidative Stress" @default.
- W2417470619 cites W1581414347 @default.
- W2417470619 cites W1775749144 @default.
- W2417470619 cites W1935339402 @default.
- W2417470619 cites W1966455349 @default.
- W2417470619 cites W1975980695 @default.
- W2417470619 cites W2000245094 @default.
- W2417470619 cites W2001977036 @default.
- W2417470619 cites W2015622540 @default.
- W2417470619 cites W2027135170 @default.
- W2417470619 cites W2031605124 @default.
- W2417470619 cites W2031851097 @default.
- W2417470619 cites W2069655299 @default.
- W2417470619 cites W2418814141 @default.
- W2417470619 doi "https://doi.org/10.1177/030089168807400601" @default.
- W2417470619 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3232205" @default.
- W2417470619 hasPublicationYear "1988" @default.
- W2417470619 type Work @default.
- W2417470619 sameAs 2417470619 @default.
- W2417470619 citedByCount "4" @default.
- W2417470619 crossrefType "journal-article" @default.
- W2417470619 hasAuthorship W2417470619A5032704680 @default.
- W2417470619 hasAuthorship W2417470619A5036064889 @default.
- W2417470619 hasConcept C158086472 @default.
- W2417470619 hasConcept C162008176 @default.
- W2417470619 hasConcept C165069038 @default.
- W2417470619 hasConcept C181199279 @default.
- W2417470619 hasConcept C185592680 @default.
- W2417470619 hasConcept C203580378 @default.
- W2417470619 hasConcept C2776151105 @default.
- W2417470619 hasConcept C2778004101 @default.
- W2417470619 hasConcept C2778760513 @default.
- W2417470619 hasConcept C2780829032 @default.
- W2417470619 hasConcept C538909803 @default.
- W2417470619 hasConcept C55493867 @default.
- W2417470619 hasConcept C98539663 @default.
- W2417470619 hasConceptScore W2417470619C158086472 @default.
- W2417470619 hasConceptScore W2417470619C162008176 @default.
- W2417470619 hasConceptScore W2417470619C165069038 @default.
- W2417470619 hasConceptScore W2417470619C181199279 @default.
- W2417470619 hasConceptScore W2417470619C185592680 @default.
- W2417470619 hasConceptScore W2417470619C203580378 @default.
- W2417470619 hasConceptScore W2417470619C2776151105 @default.
- W2417470619 hasConceptScore W2417470619C2778004101 @default.
- W2417470619 hasConceptScore W2417470619C2778760513 @default.
- W2417470619 hasConceptScore W2417470619C2780829032 @default.
- W2417470619 hasConceptScore W2417470619C538909803 @default.
- W2417470619 hasConceptScore W2417470619C55493867 @default.
- W2417470619 hasConceptScore W2417470619C98539663 @default.
- W2417470619 hasIssue "6" @default.
- W2417470619 hasLocation W24174706191 @default.
- W2417470619 hasLocation W24174706192 @default.
- W2417470619 hasOpenAccess W2417470619 @default.
- W2417470619 hasPrimaryLocation W24174706191 @default.
- W2417470619 hasRelatedWork W1170408505 @default.
- W2417470619 hasRelatedWork W2007897359 @default.
- W2417470619 hasRelatedWork W2020984542 @default.
- W2417470619 hasRelatedWork W2076007155 @default.
- W2417470619 hasRelatedWork W2076672539 @default.
- W2417470619 hasRelatedWork W2426096361 @default.
- W2417470619 hasRelatedWork W2460037499 @default.
- W2417470619 hasRelatedWork W2559508552 @default.
- W2417470619 hasRelatedWork W2611693510 @default.
- W2417470619 hasRelatedWork W786125826 @default.
- W2417470619 hasVolume "74" @default.
- W2417470619 isParatext "false" @default.
- W2417470619 isRetracted "false" @default.
- W2417470619 magId "2417470619" @default.
- W2417470619 workType "article" @default.