Matches in SemOpenAlex for { <https://semopenalex.org/work/W2417757772> ?p ?o ?g. }
Showing items 1 to 58 of
58
with 100 items per page.
- W2417757772 endingPage "80" @default.
- W2417757772 startingPage "269" @default.
- W2417757772 abstract "The osmotic reflection coefficient (sigma) of the pulmonary microvessels in sheep was estimated after a preparative trauma, and the effect of a single, high (30 mg kg -1 b.w.) dose of methylprednisolone (MP) (n = 7) compared to a dose of normal saline (S) (n = 8) was evaluated. After bilateral thoracotomies for lung lymph cannulation and placement of a balloon catheter in the left atrium, the animals were followed during anesthesia for 1 hour. Left atrial pressure (Pla) was then increased and 2 levels of filtration-independent lymph to plasma protein concentration ratio (L/P) were recorded. After the operation leukocyte and platelet counts in both groups decreased significantly. Lung lymph flow (QL) increased during the first hour without hemodynamic changes, whereas L/P decreased in the MP group but was unaffected in the S group. Partial pressure of oxygen (PaO2) was spontaneously improved postoperatively in the MP group but remained unchanged in the S group. The 2 levels of filtration-independent L/P were reached at Pla 28.7 +/- 2.8 and 34.3 +/- 1.6 mm Hg in the MP group and 25.6 +/- 2.2 and 31.3 +/- 1.3 mm Hg in the S group. QL increased by 500 +/- 80% (n = 7) and 930 +/- 210% (n = 7) at the 2 levels of increased Pla with unchanged L/P at 0.44 +/- 0.03 and 0.46 +/- 0.04, respectively, in the MP group. Corresponding values in the S group were a 590 +/- 160 (n = 5) and 730 +/- 180% (n = 3) increase in QL with L/P 0.41 +/- 0.02 and 0.40 +/- 0.03, respectively. sigma in the MP group was 0.54 +/- 0.04, and sigma in the S group was 0.62 +/- 0.02, which was not significantly different. Thus pretreatment with MP did not prevent the development of a permeability lesion following surgical pulmonary trauma, but an early minor protective effect of MP could not be ruled out." @default.
- W2417757772 created "2016-06-24" @default.
- W2417757772 creator A5020049163 @default.
- W2417757772 creator A5056551181 @default.
- W2417757772 creator A5061606927 @default.
- W2417757772 date "1986-01-01" @default.
- W2417757772 modified "2023-09-27" @default.
- W2417757772 title "No protection in sheep by high-dose methylprednisolone against pulmonary microvascular injury following trauma." @default.
- W2417757772 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3791576" @default.
- W2417757772 hasPublicationYear "1986" @default.
- W2417757772 type Work @default.
- W2417757772 sameAs 2417757772 @default.
- W2417757772 citedByCount "0" @default.
- W2417757772 crossrefType "journal-article" @default.
- W2417757772 hasAuthorship W2417757772A5020049163 @default.
- W2417757772 hasAuthorship W2417757772A5056551181 @default.
- W2417757772 hasAuthorship W2417757772A5061606927 @default.
- W2417757772 hasConcept C126322002 @default.
- W2417757772 hasConcept C126894567 @default.
- W2417757772 hasConcept C142724271 @default.
- W2417757772 hasConcept C178853913 @default.
- W2417757772 hasConcept C2777397205 @default.
- W2417757772 hasConcept C2777714996 @default.
- W2417757772 hasConcept C2779720271 @default.
- W2417757772 hasConcept C2780372218 @default.
- W2417757772 hasConcept C42219234 @default.
- W2417757772 hasConcept C71924100 @default.
- W2417757772 hasConceptScore W2417757772C126322002 @default.
- W2417757772 hasConceptScore W2417757772C126894567 @default.
- W2417757772 hasConceptScore W2417757772C142724271 @default.
- W2417757772 hasConceptScore W2417757772C178853913 @default.
- W2417757772 hasConceptScore W2417757772C2777397205 @default.
- W2417757772 hasConceptScore W2417757772C2777714996 @default.
- W2417757772 hasConceptScore W2417757772C2779720271 @default.
- W2417757772 hasConceptScore W2417757772C2780372218 @default.
- W2417757772 hasConceptScore W2417757772C42219234 @default.
- W2417757772 hasConceptScore W2417757772C71924100 @default.
- W2417757772 hasIssue "4" @default.
- W2417757772 hasLocation W24177577721 @default.
- W2417757772 hasOpenAccess W2417757772 @default.
- W2417757772 hasPrimaryLocation W24177577721 @default.
- W2417757772 hasRelatedWork W1974217680 @default.
- W2417757772 hasRelatedWork W1992412419 @default.
- W2417757772 hasRelatedWork W1993815346 @default.
- W2417757772 hasRelatedWork W2018730194 @default.
- W2417757772 hasRelatedWork W2082470894 @default.
- W2417757772 hasRelatedWork W2122463516 @default.
- W2417757772 hasRelatedWork W2306027249 @default.
- W2417757772 hasRelatedWork W2369728676 @default.
- W2417757772 hasRelatedWork W2408923631 @default.
- W2417757772 hasRelatedWork W2413573603 @default.
- W2417757772 hasVolume "20" @default.
- W2417757772 isParatext "false" @default.
- W2417757772 isRetracted "false" @default.
- W2417757772 magId "2417757772" @default.
- W2417757772 workType "article" @default.