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- W2417839600 abstract "Obesity greatly increases the risk for cardiovascular, metabolic, and renal diseases and is one of the most significant and preventable causes of increased blood pressure (BP) in patients with essential hypertension. This review highlights recent advances in our understanding of central nervous system (CNS) signaling pathways that contribute to the etiology and pathogenesis of obesity-induced hypertension. We discuss the role of excess adiposity and activation of the brain leptin-melanocortin system in causing increased sympathetic activity in obesity. In addition, we highlight other potential brain mechanisms by which increased weight gain modulates metabolic and cardiovascular functions. Unraveling the CNS mechanisms responsible for increased sympathetic activation and hypertension and how circulating hormones activate brain signaling pathways to control BP offer potentially important therapeutic targets for obesity and hypertension." @default.
- W2417839600 created "2016-06-24" @default.
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- W2417839600 date "2016-06-04" @default.
- W2417839600 modified "2023-10-16" @default.
- W2417839600 title "Obesity-Induced Hypertension: Brain Signaling Pathways" @default.
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- W2417839600 cites W1971580497 @default.
- W2417839600 cites W1972335051 @default.
- W2417839600 cites W1974475131 @default.
- W2417839600 cites W1975214074 @default.
- W2417839600 cites W1976029372 @default.
- W2417839600 cites W1984546941 @default.
- W2417839600 cites W1997489762 @default.
- W2417839600 cites W1998262683 @default.
- W2417839600 cites W2004830232 @default.
- W2417839600 cites W2012416246 @default.
- W2417839600 cites W2012782405 @default.
- W2417839600 cites W2013332206 @default.
- W2417839600 cites W2015104765 @default.
- W2417839600 cites W2020018784 @default.
- W2417839600 cites W2020172718 @default.
- W2417839600 cites W2021305708 @default.
- W2417839600 cites W2024802365 @default.
- W2417839600 cites W2025517143 @default.
- W2417839600 cites W2040428630 @default.
- W2417839600 cites W2041955330 @default.
- W2417839600 cites W2045999047 @default.
- W2417839600 cites W2046261890 @default.
- W2417839600 cites W2047118253 @default.
- W2417839600 cites W2051559850 @default.
- W2417839600 cites W2054523815 @default.
- W2417839600 cites W2058974627 @default.
- W2417839600 cites W2059063316 @default.
- W2417839600 cites W2061072142 @default.
- W2417839600 cites W2061340727 @default.
- W2417839600 cites W2062166677 @default.
- W2417839600 cites W2064109637 @default.
- W2417839600 cites W2066037847 @default.
- W2417839600 cites W2067956022 @default.
- W2417839600 cites W2072206476 @default.
- W2417839600 cites W2072436009 @default.
- W2417839600 cites W2076240888 @default.
- W2417839600 cites W2078207715 @default.
- W2417839600 cites W2080418085 @default.
- W2417839600 cites W2081765499 @default.
- W2417839600 cites W2083921588 @default.
- W2417839600 cites W2088864173 @default.
- W2417839600 cites W2089861942 @default.
- W2417839600 cites W2091706768 @default.
- W2417839600 cites W2093433413 @default.
- W2417839600 cites W2094878829 @default.
- W2417839600 cites W2096229046 @default.
- W2417839600 cites W2096239442 @default.
- W2417839600 cites W2097090923 @default.
- W2417839600 cites W2099547572 @default.
- W2417839600 cites W2105572243 @default.
- W2417839600 cites W2118458077 @default.
- W2417839600 cites W2119850839 @default.
- W2417839600 cites W2119959145 @default.
- W2417839600 cites W2126412697 @default.
- W2417839600 cites W2129899139 @default.
- W2417839600 cites W2132325669 @default.
- W2417839600 cites W2132681327 @default.
- W2417839600 cites W2133059852 @default.
- W2417839600 cites W2133576470 @default.
- W2417839600 cites W2135757151 @default.
- W2417839600 cites W2136824109 @default.
- W2417839600 cites W2138538255 @default.
- W2417839600 cites W2143237504 @default.
- W2417839600 cites W2145600837 @default.
- W2417839600 cites W2147984307 @default.
- W2417839600 cites W2148594052 @default.
- W2417839600 cites W2151009383 @default.
- W2417839600 cites W2152899311 @default.
- W2417839600 cites W2160147681 @default.
- W2417839600 cites W2160742869 @default.
- W2417839600 cites W2164384489 @default.
- W2417839600 cites W2166751358 @default.
- W2417839600 cites W2188953028 @default.
- W2417839600 cites W2289989491 @default.
- W2417839600 cites W2319361543 @default.
- W2417839600 cites W2332505512 @default.
- W2417839600 cites W2383859278 @default.
- W2417839600 cites W2401554380 @default.
- W2417839600 cites W2546647298 @default.
- W2417839600 cites W3144014357 @default.
- W2417839600 cites W4248390398 @default.
- W2417839600 cites W285502117 @default.
- W2417839600 doi "https://doi.org/10.1007/s11906-016-0658-1" @default.
- W2417839600 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5448788" @default.