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• W2417856131 abstract "Mixed states are complex manifestations of bipolar disorders. Pathophysiology of mixed states remains unclear. Several models have been proposed to understand the mechanisms underlying these mood states. These models describe mixed state either as a combinaison of depression and mania, as well as a transition between mania and depression, or mixed state as a severe type of depression or mania. Pathophysiological hypotheses involve temperaments or some personality disorders, psychiatric comorbidities as well as substance use disorders, or thyroid dysfunction. However, the formal demonstration of any specific genetic vulnerability to mixed state has not yet been provided." @default.
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• W2417856131 date "2013-12-01" @default.
• W2417856131 modified "2023-10-14" @default.
• W2417856131 title "Modèles physiopathologiques des états mixtes" @default.
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• W2417856131 doi "https://doi.org/10.1016/s0013-7006(13)70117-9" @default.
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