Matches in SemOpenAlex for { <https://semopenalex.org/work/W2417885529> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2417885529 endingPage "6" @default.
- W2417885529 startingPage "50" @default.
- W2417885529 abstract "The purpose was to evaluate the usefulness of serum Cyfra 21.1 assay for the monitoring of patients with uterine cervix cancer.Pre-treatment sera and complete follow-up of the patients were available for SCC and Cyfra 21.1 for 79 patients Another group of 50 patients was studied to evaluate the specificity, sensitivity, negative or positive predictive values of the markers. The cut-off value for Cyfra 21.1 (1.1 ng/ml) was established by ROC curve analysis.A positive or negative concordance between SCC and Cyfra 21.1 was observed in 65.8% of the cases. Positive SCC and negative Cyfra 21.1 were found in 22.8% of the sera, while the inverse was observed in 11.4% of the cases. The mean concentrations of SCC and Cyfra 21.1 were correlated to FIGO stages, with Cyfra 21.1 being elevated in 100% of stages III and IV. Cyfra 21.1 was also correlated with the extension of the cancer, and to the presence of metastases. The mean concentrations of both markers were significantly higher in the sera of patients with constant progression (P < or = 0.0019). Analysis of 186 results from 91 patients followed-up with a median of 3.29 years showed a sensitivity of 89.5% for Cyfra 21.1, 75.0% for SCC, and a specificity of 86.4% and 99.1%, respectively. The positive predictive values were 91.9% for Cyfra 21.1 and 98.3% for SCC, and the negative predictive values 92.7% and 85.2%, respectively. Median lead times, calculated from the records of 18 selected patients with complete resection of the tumour, were found to be 60 days for Cyfra 21.1 and 50 days for SCC (P > 0.05).In cervical cancer Cyfra 21.1 is very well-correlated to the tumour burden and the extent of the disease. In the case of recurrence, this marker rises more often than SCC. We therefore propose the use of Cyfra 21.1 for the monitoring of cervical cancer." @default.
- W2417885529 created "2016-06-24" @default.
- W2417885529 creator A5010354914 @default.
- W2417885529 creator A5034007188 @default.
- W2417885529 creator A5058322158 @default.
- W2417885529 creator A5061100031 @default.
- W2417885529 date "1998-01-01" @default.
- W2417885529 modified "2023-10-04" @default.
- W2417885529 title "Cancer of the uterine cervix: sensitivity and specificity of serum Cyfra 21.1 determinations." @default.
- W2417885529 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9476060" @default.
- W2417885529 hasPublicationYear "1998" @default.
- W2417885529 type Work @default.
- W2417885529 sameAs 2417885529 @default.
- W2417885529 citedByCount "6" @default.
- W2417885529 countsByYear W24178855292012 @default.
- W2417885529 countsByYear W24178855292017 @default.
- W2417885529 crossrefType "journal-article" @default.
- W2417885529 hasAuthorship W2417885529A5010354914 @default.
- W2417885529 hasAuthorship W2417885529A5034007188 @default.
- W2417885529 hasAuthorship W2417885529A5058322158 @default.
- W2417885529 hasAuthorship W2417885529A5061100031 @default.
- W2417885529 hasConcept C121608353 @default.
- W2417885529 hasConcept C126322002 @default.
- W2417885529 hasConcept C142724271 @default.
- W2417885529 hasConcept C160798450 @default.
- W2417885529 hasConcept C2777546739 @default.
- W2417885529 hasConcept C2777740455 @default.
- W2417885529 hasConcept C29456083 @default.
- W2417885529 hasConcept C2992879611 @default.
- W2417885529 hasConcept C3019719930 @default.
- W2417885529 hasConcept C53789813 @default.
- W2417885529 hasConcept C71924100 @default.
- W2417885529 hasConcept C90924648 @default.
- W2417885529 hasConceptScore W2417885529C121608353 @default.
- W2417885529 hasConceptScore W2417885529C126322002 @default.
- W2417885529 hasConceptScore W2417885529C142724271 @default.
- W2417885529 hasConceptScore W2417885529C160798450 @default.
- W2417885529 hasConceptScore W2417885529C2777546739 @default.
- W2417885529 hasConceptScore W2417885529C2777740455 @default.
- W2417885529 hasConceptScore W2417885529C29456083 @default.
- W2417885529 hasConceptScore W2417885529C2992879611 @default.
- W2417885529 hasConceptScore W2417885529C3019719930 @default.
- W2417885529 hasConceptScore W2417885529C53789813 @default.
- W2417885529 hasConceptScore W2417885529C71924100 @default.
- W2417885529 hasConceptScore W2417885529C90924648 @default.
- W2417885529 hasIssue "1" @default.
- W2417885529 hasLocation W24178855291 @default.
- W2417885529 hasOpenAccess W2417885529 @default.
- W2417885529 hasPrimaryLocation W24178855291 @default.
- W2417885529 hasRelatedWork W1530145183 @default.
- W2417885529 hasRelatedWork W2024373227 @default.
- W2417885529 hasRelatedWork W2045566574 @default.
- W2417885529 hasRelatedWork W2122819346 @default.
- W2417885529 hasRelatedWork W2131111298 @default.
- W2417885529 hasRelatedWork W2145848930 @default.
- W2417885529 hasRelatedWork W2184739936 @default.
- W2417885529 hasRelatedWork W2536553653 @default.
- W2417885529 hasRelatedWork W2591175961 @default.
- W2417885529 hasRelatedWork W4319058211 @default.
- W2417885529 hasVolume "19" @default.
- W2417885529 isParatext "false" @default.
- W2417885529 isRetracted "false" @default.
- W2417885529 magId "2417885529" @default.
- W2417885529 workType "article" @default.