Matches in SemOpenAlex for { <https://semopenalex.org/work/W2417968420> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2417968420 abstract "Background: The main strategy for rolling back malaria in Africa is prompt, presumptive treatment of fever among those at risk. Most fevers in Africa are treated first with antipyretic or antimalarial drugs obtained from the retail sector. The objectives of the thesis were to understand retail provision of antimalarial drugs, drug use patterns and quality in four communities in Kenya to enable an exploration of impediments to effective antimalarial drug use in Kenya and how these might be redressed in the national antimalarial drug policy. Methods: The thesis used an eclectic mix of methods: from review of policy documents; key informant interviews; laboratory-based pharmaceutical analytical techniques; mathematical modeling of effectiveness; to structured questionnaires administered to households/retailers in four districts of Kenya. Results: The community survey revealed that less than 3% of children below five years accessed sulfadoxine/pyrimethamine (SP), the first-line drug. Adult and paediatric doses of SP and amodiaquine (AQ, second-line) in the retail retail sector were less than one US dollar; that of the new first-line drug, artemether-lumefantrine (ART-LUM) was eight US dollars. Less than a third of the retailers knew the correct dose of AQ for an adult and even less (2%) could state the correct dose for a child of 2 years. About 41% of SP and AQ products sampled from the retail sector were sub-standard. The modeled effectiveness of SP and AQ was found to be 51 and 45%, respectively, when drug quality, use, and adherence were taken into consideration; that of ART-LUM was approximately 85%. Conclusions: Effective drugs are not a panacea to therapy of malaria if they remain inaccessible to rural populations at risk in Kenya. The RBM targets on prompt, effective treatment of fevers are unlikely to be met without an increased investment in behaviour change initiatives and provision of effective and affordable therapeutics at all levels of the health service, including the retail sector." @default.
- W2417968420 created "2016-06-24" @default.
- W2417968420 creator A5083642348 @default.
- W2417968420 date "2005-07-04" @default.
- W2417968420 modified "2023-09-24" @default.
- W2417968420 title "Range, quality, and costs of antimalarial drugs available in the retail sector in Kenya" @default.
- W2417968420 doi "https://doi.org/10.21954/ou.ro.000101e2" @default.
- W2417968420 hasPublicationYear "2005" @default.
- W2417968420 type Work @default.
- W2417968420 sameAs 2417968420 @default.
- W2417968420 citedByCount "1" @default.
- W2417968420 crossrefType "dissertation" @default.
- W2417968420 hasAuthorship W2417968420A5083642348 @default.
- W2417968420 hasConcept C10138342 @default.
- W2417968420 hasConcept C109168655 @default.
- W2417968420 hasConcept C111472728 @default.
- W2417968420 hasConcept C138885662 @default.
- W2417968420 hasConcept C144133560 @default.
- W2417968420 hasConcept C162853370 @default.
- W2417968420 hasConcept C203014093 @default.
- W2417968420 hasConcept C2776120307 @default.
- W2417968420 hasConcept C2776992834 @default.
- W2417968420 hasConcept C2777425658 @default.
- W2417968420 hasConcept C2778048844 @default.
- W2417968420 hasConcept C2778118209 @default.
- W2417968420 hasConcept C2778371730 @default.
- W2417968420 hasConcept C2779530757 @default.
- W2417968420 hasConcept C2780035454 @default.
- W2417968420 hasConcept C2780780316 @default.
- W2417968420 hasConcept C556039675 @default.
- W2417968420 hasConcept C71924100 @default.
- W2417968420 hasConcept C98274493 @default.
- W2417968420 hasConcept C99454951 @default.
- W2417968420 hasConceptScore W2417968420C10138342 @default.
- W2417968420 hasConceptScore W2417968420C109168655 @default.
- W2417968420 hasConceptScore W2417968420C111472728 @default.
- W2417968420 hasConceptScore W2417968420C138885662 @default.
- W2417968420 hasConceptScore W2417968420C144133560 @default.
- W2417968420 hasConceptScore W2417968420C162853370 @default.
- W2417968420 hasConceptScore W2417968420C203014093 @default.
- W2417968420 hasConceptScore W2417968420C2776120307 @default.
- W2417968420 hasConceptScore W2417968420C2776992834 @default.
- W2417968420 hasConceptScore W2417968420C2777425658 @default.
- W2417968420 hasConceptScore W2417968420C2778048844 @default.
- W2417968420 hasConceptScore W2417968420C2778118209 @default.
- W2417968420 hasConceptScore W2417968420C2778371730 @default.
- W2417968420 hasConceptScore W2417968420C2779530757 @default.
- W2417968420 hasConceptScore W2417968420C2780035454 @default.
- W2417968420 hasConceptScore W2417968420C2780780316 @default.
- W2417968420 hasConceptScore W2417968420C556039675 @default.
- W2417968420 hasConceptScore W2417968420C71924100 @default.
- W2417968420 hasConceptScore W2417968420C98274493 @default.
- W2417968420 hasConceptScore W2417968420C99454951 @default.
- W2417968420 hasLocation W24179684201 @default.
- W2417968420 hasOpenAccess W2417968420 @default.
- W2417968420 hasPrimaryLocation W24179684201 @default.
- W2417968420 hasRelatedWork W119075302 @default.
- W2417968420 hasRelatedWork W1771115864 @default.
- W2417968420 hasRelatedWork W1980793725 @default.
- W2417968420 hasRelatedWork W1985725215 @default.
- W2417968420 hasRelatedWork W1988260240 @default.
- W2417968420 hasRelatedWork W1991947937 @default.
- W2417968420 hasRelatedWork W2031585245 @default.
- W2417968420 hasRelatedWork W2083613508 @default.
- W2417968420 hasRelatedWork W2100545214 @default.
- W2417968420 hasRelatedWork W2122713918 @default.
- W2417968420 hasRelatedWork W2135542480 @default.
- W2417968420 hasRelatedWork W2158535002 @default.
- W2417968420 hasRelatedWork W2160906605 @default.
- W2417968420 hasRelatedWork W2163483188 @default.
- W2417968420 hasRelatedWork W2236296643 @default.
- W2417968420 hasRelatedWork W2531531861 @default.
- W2417968420 hasRelatedWork W3175278115 @default.
- W2417968420 hasRelatedWork W97986785 @default.
- W2417968420 hasRelatedWork W2295787639 @default.
- W2417968420 hasRelatedWork W2584610648 @default.
- W2417968420 isParatext "false" @default.
- W2417968420 isRetracted "false" @default.
- W2417968420 magId "2417968420" @default.
- W2417968420 workType "dissertation" @default.