Matches in SemOpenAlex for { <https://semopenalex.org/work/W2417990609> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2417990609 startingPage "251" @default.
- W2417990609 abstract "UNLABELLED Alcohol misuse impairs the glycosylation, secretion and metabolism of glycoproteins what may influence on their blood concentration. THE AIM OF THIS STUDY To evaluate the effect of alcohol abuse on the level of sialylated glycoproteins such as: alpha1-antitripsin, alpha1-acid glycoprotein, haptoglobin, ceruloplasmin, transferrin, complement C3 protein, immunoglobulin G and fibrinogen in the blood. MATERIAL AND METHODS The study was carried out in 156 alcohol dependent men, who were divided into 6 subgroups according to three criteria: the amounts of weekly alcohol intake, the time of abstinence before examination and the period of last drinking; and in 35 healthy social drinkers. The concentration of glycoproteins was measured using an immunoturbidimetric methods. RESULTS There were changes in the serum levels of 3 from 8 tested glycoproteins in alcohol dependent men. The concentrations of alantitripsin and alpha1-acid glycoprotein were increased, but of transferrin - decreased. The analysis of glycoproteins according to the history of alcohol abuse showed that alpha1-acid glycoprotein, ceruloplasmin and complement C3 protein were sensitive to the amounts of weekly alcohol intake. The alpha1-antitripsin, as the only, was sensitive to the period of last drinking. None of the tested glycoproteins was sensitive to the time of abstinence before examination. CONCLUSION Alcohol abuse leads to the alterations of sialylated glycoproteins concentrations in the blood, what is a proof of disturbances in their synthesis in the liver. The direction of these changes is typical of acute phase reaction. The quantitative alterations may accompany the qualitative changes in the form of glycosylation disturbances, what is documented by the increased concentration of low sialylated isoforms of transfferin." @default.
- W2417990609 created "2016-06-24" @default.
- W2417990609 creator A5006388276 @default.
- W2417990609 creator A5026285740 @default.
- W2417990609 creator A5031419790 @default.
- W2417990609 creator A5051807885 @default.
- W2417990609 creator A5068740250 @default.
- W2417990609 date "2007-10-01" @default.
- W2417990609 modified "2023-09-25" @default.
- W2417990609 title "The concentration of sialylated glycoproteins in the sera of alcohol dependent men" @default.
- W2417990609 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18293845" @default.
- W2417990609 hasPublicationYear "2007" @default.
- W2417990609 type Work @default.
- W2417990609 sameAs 2417990609 @default.
- W2417990609 citedByCount "0" @default.
- W2417990609 crossrefType "journal-article" @default.
- W2417990609 hasAuthorship W2417990609A5006388276 @default.
- W2417990609 hasAuthorship W2417990609A5026285740 @default.
- W2417990609 hasAuthorship W2417990609A5031419790 @default.
- W2417990609 hasAuthorship W2417990609A5051807885 @default.
- W2417990609 hasAuthorship W2417990609A5068740250 @default.
- W2417990609 hasConcept C108625454 @default.
- W2417990609 hasConcept C118552586 @default.
- W2417990609 hasConcept C126322002 @default.
- W2417990609 hasConcept C134018914 @default.
- W2417990609 hasConcept C146543888 @default.
- W2417990609 hasConcept C185592680 @default.
- W2417990609 hasConcept C206396517 @default.
- W2417990609 hasConcept C22814914 @default.
- W2417990609 hasConcept C2776914184 @default.
- W2417990609 hasConcept C2777313579 @default.
- W2417990609 hasConcept C2780931562 @default.
- W2417990609 hasConcept C2781066024 @default.
- W2417990609 hasConcept C28452662 @default.
- W2417990609 hasConcept C30787643 @default.
- W2417990609 hasConcept C55493867 @default.
- W2417990609 hasConcept C57194454 @default.
- W2417990609 hasConcept C71924100 @default.
- W2417990609 hasConceptScore W2417990609C108625454 @default.
- W2417990609 hasConceptScore W2417990609C118552586 @default.
- W2417990609 hasConceptScore W2417990609C126322002 @default.
- W2417990609 hasConceptScore W2417990609C134018914 @default.
- W2417990609 hasConceptScore W2417990609C146543888 @default.
- W2417990609 hasConceptScore W2417990609C185592680 @default.
- W2417990609 hasConceptScore W2417990609C206396517 @default.
- W2417990609 hasConceptScore W2417990609C22814914 @default.
- W2417990609 hasConceptScore W2417990609C2776914184 @default.
- W2417990609 hasConceptScore W2417990609C2777313579 @default.
- W2417990609 hasConceptScore W2417990609C2780931562 @default.
- W2417990609 hasConceptScore W2417990609C2781066024 @default.
- W2417990609 hasConceptScore W2417990609C28452662 @default.
- W2417990609 hasConceptScore W2417990609C30787643 @default.
- W2417990609 hasConceptScore W2417990609C55493867 @default.
- W2417990609 hasConceptScore W2417990609C57194454 @default.
- W2417990609 hasConceptScore W2417990609C71924100 @default.
- W2417990609 hasIssue "136" @default.
- W2417990609 hasLocation W24179906091 @default.
- W2417990609 hasLocation W24179906092 @default.
- W2417990609 hasOpenAccess W2417990609 @default.
- W2417990609 hasPrimaryLocation W24179906091 @default.
- W2417990609 hasRelatedWork W1652084352 @default.
- W2417990609 hasRelatedWork W1920017348 @default.
- W2417990609 hasRelatedWork W1963743345 @default.
- W2417990609 hasRelatedWork W1973400391 @default.
- W2417990609 hasRelatedWork W2008247941 @default.
- W2417990609 hasRelatedWork W2017535660 @default.
- W2417990609 hasRelatedWork W2021077559 @default.
- W2417990609 hasRelatedWork W2113232641 @default.
- W2417990609 hasRelatedWork W2133105673 @default.
- W2417990609 hasRelatedWork W2146030096 @default.
- W2417990609 hasRelatedWork W2169726602 @default.
- W2417990609 hasRelatedWork W2200818620 @default.
- W2417990609 hasRelatedWork W2257850663 @default.
- W2417990609 hasRelatedWork W2397986358 @default.
- W2417990609 hasRelatedWork W2404767836 @default.
- W2417990609 hasRelatedWork W2415731245 @default.
- W2417990609 hasRelatedWork W2416249068 @default.
- W2417990609 hasRelatedWork W2418677857 @default.
- W2417990609 hasRelatedWork W2793091818 @default.
- W2417990609 hasRelatedWork W2182485000 @default.
- W2417990609 hasVolume "23" @default.
- W2417990609 isParatext "false" @default.
- W2417990609 isRetracted "false" @default.
- W2417990609 magId "2417990609" @default.
- W2417990609 workType "article" @default.