FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2418117017> ?p ?o ?g. }

• W2418117017 endingPage "e0156577" @default.
• W2418117017 startingPage "e0156577" @default.
• W2418117017 abstract "Clostridium difficile infection is the most common hospital-acquired infection. Besides infected patients, carriers have emerged as a key player in C. difficile epidemiology. In this study, we evaluated the impact of identifying and isolating carriers upon hospital admission on the incidence of CDI incidence and hospital-acquired C. difficile colonization, as a single policy and as part of bundle approaches. We simulated C. difficile transmission using a stochastic mathematical approach, considering the contribution of carriers based on published literature. In the baseline scenario, CDI incidence was 6.18/1,000 admissions (95% CI, 5.72–6.65), simulating reported estimates from U.S. hospital discharges. The acquisition rate of C. difficile carriage was 9.72/1,000 admissions (95% CI, 9.15–10.31). Screening and isolation of colonized patients on admission to the hospital decreased CDI incidence to 4.99/1,000 admissions (95% CI, 4.59–5.42; relative reduction (RR) = 19.1%) and led to 36.2% reduction in the rate of hospital-acquired colonization. Simulating an antimicrobial stewardship program reduced CDI rate to 2.35/1,000 admissions (95% CI, 2.07–2.65). In sensitivity analysis, CDI incidence was less than 2.32/1,000 admissions (RR = 62.4%) in 95% of 1,000 simulations. The combined bundle, focusing on reducing C. difficile transmission from colonized patients and the individual risk of these patients to develop CDI, decreased significantly the incidence of both CDI and hospital-acquired colonization. Implementation of this bundle to current practice is expected to have an important impact in containing CDI." @default.
• W2418117017 created "2016-06-24" @default.
• W2418117017 creator A5011903299 @default.
• W2418117017 creator A5024003378 @default.
• W2418117017 creator A5039665455 @default.
• W2418117017 creator A5076505995 @default.
• W2418117017 creator A5090389995 @default.
• W2418117017 date "2016-06-03" @default.
• W2418117017 modified "2023-10-04" @default.
• W2418117017 title "Isolation of C. difficile Carriers Alone and as Part of a Bundle Approach for the Prevention of Clostridium difficile Infection (CDI): A Mathematical Model Based on Clinical Study Data" @default.
• W2418117017 cites W1966499354 @default.
• W2418117017 cites W1973790525 @default.
• W2418117017 cites W1975999946 @default.
• W2418117017 cites W1976256305 @default.
• W2418117017 cites W1987762312 @default.
• W2418117017 cites W1988972143 @default.
• W2418117017 cites W1991364004 @default.
• W2418117017 cites W1998272935 @default.
• W2418117017 cites W2005834141 @default.
• W2418117017 cites W2018059663 @default.
• W2418117017 cites W2022967441 @default.
• W2418117017 cites W2030458286 @default.
• W2418117017 cites W2037714831 @default.
• W2418117017 cites W2048866421 @default.
• W2418117017 cites W2064849446 @default.
• W2418117017 cites W2066809324 @default.
• W2418117017 cites W2070316988 @default.
• W2418117017 cites W2071054182 @default.
• W2418117017 cites W2077578991 @default.
• W2418117017 cites W2082046334 @default.
• W2418117017 cites W2088092352 @default.
• W2418117017 cites W2097330653 @default.
• W2418117017 cites W2099141037 @default.
• W2418117017 cites W2102295825 @default.
• W2418117017 cites W2104948212 @default.
• W2418117017 cites W2112968037 @default.
• W2418117017 cites W2115404062 @default.
• W2418117017 cites W2123366827 @default.
• W2418117017 cites W2127424257 @default.
• W2418117017 cites W2134091331 @default.
• W2418117017 cites W2134500103 @default.
• W2418117017 cites W2147741767 @default.
• W2418117017 cites W2148425673 @default.
• W2418117017 cites W2153155854 @default.
• W2418117017 cites W2155278947 @default.
• W2418117017 cites W2155800098 @default.
• W2418117017 cites W2158871837 @default.
• W2418117017 cites W2158945684 @default.
• W2418117017 cites W2165065971 @default.
• W2418117017 cites W2165188084 @default.
• W2418117017 cites W2165484046 @default.
• W2418117017 cites W2166660180 @default.
• W2418117017 cites W2328690882 @default.
• W2418117017 cites W2341427843 @default.
• W2418117017 cites W2810715112 @default.
• W2418117017 cites W4250063519 @default.
• W2418117017 cites W4302331569 @default.
• W2418117017 doi "https://doi.org/10.1371/journal.pone.0156577" @default.
• W2418117017 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4892551" @default.
• W2418117017 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27258068" @default.
• W2418117017 hasPublicationYear "2016" @default.
• W2418117017 type Work @default.
• W2418117017 sameAs 2418117017 @default.
• W2418117017 citedByCount "31" @default.
• W2418117017 countsByYear W24181170172016 @default.
• W2418117017 countsByYear W24181170172017 @default.
• W2418117017 countsByYear W24181170172018 @default.
• W2418117017 countsByYear W24181170172019 @default.
• W2418117017 countsByYear W24181170172020 @default.
• W2418117017 countsByYear W24181170172021 @default.
• W2418117017 countsByYear W24181170172022 @default.
• W2418117017 countsByYear W24181170172023 @default.
• W2418117017 crossrefType "journal-article" @default.
• W2418117017 hasAuthorship W2418117017A5011903299 @default.
• W2418117017 hasAuthorship W2418117017A5024003378 @default.
• W2418117017 hasAuthorship W2418117017A5039665455 @default.
• W2418117017 hasAuthorship W2418117017A5076505995 @default.
• W2418117017 hasAuthorship W2418117017A5090389995 @default.
• W2418117017 hasBestOaLocation W24181170171 @default.
• W2418117017 hasConcept C107130276 @default.
• W2418117017 hasConcept C119599485 @default.
• W2418117017 hasConcept C120665830 @default.
• W2418117017 hasConcept C121332964 @default.
• W2418117017 hasConcept C126322002 @default.
• W2418117017 hasConcept C127413603 @default.
• W2418117017 hasConcept C142724271 @default.
• W2418117017 hasConcept C166888038 @default.
• W2418117017 hasConcept C177713679 @default.
• W2418117017 hasConcept C194828623 @default.
• W2418117017 hasConcept C2775941552 @default.
• W2418117017 hasConcept C2776040555 @default.
• W2418117017 hasConcept C2776927270 @default.
• W2418117017 hasConcept C2994496256 @default.
• W2418117017 hasConcept C3019428505 @default.
• W2418117017 hasConcept C32762888 @default.
• W2418117017 hasConcept C501593827 @default.
• W2418117017 hasConcept C61511704 @default.
• W2418117017 hasConcept C71924100 @default.

• next