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- W2418410441 abstract "The protein synthesis stimulating activity of the cytosol from the livers of rats of different age was tested in a cell-free system using washed rat liver polysomes. This activity declines significantly with increasing age. From experiments on the effect of addition of purified eIF-2 to the cell-free polysomal/cytosolic systems as well as from changes in the Met-tRNA(f) binding activity of the cytosol it is concluded that alterations in eIF-2 play an essential role in the decrease of protein synthesis with increasing age." @default.
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- W2418410441 date "1987-01-01" @default.
- W2418410441 modified "2023-09-27" @default.
- W2418410441 title "Age dependent changes in the activity of the cytosolic fraction from rat liver to stimulate polysomal protein synthesis and the role of initiation factor eIF-2." @default.
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