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- W2418577897 abstract "We have investigated the effects of AgCl and AgNO 3 on the Ca v 3.1 calcium channels stably expressed in the HEK 293 cells. Ca 2 + was used as a charge carrier. Both forms of Ag + blocked the Ca v 3.1 channel and negativelyshifted the I-V relations in a concentration-dependent manner. The inhibition of current amplitude by AgCl was voltage-dependent and increased with increasing amplitude of the depolarizing pulse. Furthermore, AgCl but not AgNO 3 accelerated the kinetics of current activation. No effect on current inactivation or steady-state inactivation of the channel was observed for AgCl or AgNO 3 ." @default.
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- W2418577897 date "2003-12-01" @default.
- W2418577897 modified "2023-10-10" @default.
- W2418577897 title "Inhibition of Cav3.1 channel by silver ions." @default.
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