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- W2418580373 abstract "We studied the degree of interruption of the enterohepatic circulation of bile salts in patients with bile salt malabsorption after ileal resection, using a double isotope method to circumvent the problems due to absence of steady state conditions. We measured the proportion of the isotopically labeled pool of glycocholate and glycochenodeoxycholate present before a standard evening meal, which was still present in fasting bile the following morning. The proportion of glycocholate returned by the patients during this period averaged 5.8% of that returned by the control subjects, while the equivalent value for glycochenodeoxycholate was 2.3%. We conclude that in patients with ileal resection, the remaining small bowel is unable to contribute significantly in maintaining enterohepatic circulation of conjugated bile salts. In these patients, the bulk of the bile salts in the gallbladder before breakfast had been synthesized overnight." @default.
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- W2418580373 date "1974-09-01" @default.
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- W2418580373 title "Effect of One Meal on Enterohepatic Circulation of Bile Salts" @default.
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- W2418580373 doi "https://doi.org/10.1016/s0016-5085(19)32850-1" @default.
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