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- W2418717811 abstract "The objective of this study was to characterize the effects of Mo and S feeding, following inflammatory challenge in beef heifers. Twelve Braford heifers (average initial BW = 395 kg) were allocated randomly to one of two prestudy dietary treatments (depletion phase; 90 d). Treatments consisted of a daily supplement of 454 g of ground corn fortified with 0.7 g of sodium molybdate and 18.5 g of S (low-Cu; n = 6) or 454 g of ground corn alone (control; n = 6). All heifers received 57 g/d of a complete saltbased mineral devoid of supplement Cu. Following depletion, low-Cu heifers had lower (P<0.001) liver Cu concentrations compared to control (62 vs 344 ppm DM; SEM = 12.2 ppm). Following Cu depletion, heifers were moved into individual pens (114 m2) and offered access to freechoice, long-stem limpograss hay. To induce an inflammatory response, all heifers received a single subcutaneous injection (3 mL) of adjuvant (d 0). Blood samples were collected by jugular venapuncture on d 0, 2, 4, 7, 9, 11, 14, 16, 18, and 21. Plasma was harvested from blood at each collection and analyzed for concentrations of ceruloplasmin, fibrinogen, alpha-acid glycoprotein, and haptoglobin. Blood concentration of each acute-phase protein increased following adjuvant challenge. Plasma ceruloplasmin concentrations were less (P<0.001) and fibrinogen concentrations greater (P<0.001) in low-Cu than control heifers following challenge. Alpha-acid glycoprotein concentrations were less (P<0.01) in low-Cu than control heifers. Haptoglobin concentrations were not affected (P=0.21) by Cu status. These results indicate that the Cu status of beef heifers is directly linked to concentrations of acute-phase proteins both prior to and during a response to inflammatory challenge." @default.
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- W2418717811 date "2003-06-01" @default.
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- W2418717811 title "Effect of Molybdenum and Sulfur Feeding on the Acute Phase Protein Response to Inflammatory Challenge in Beef Heifers11Contribution No. R-08557 from the Florida Agriculture Experiment Station." @default.
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- W2418717811 doi "https://doi.org/10.15232/s1080-7446(15)31408-x" @default.
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