Matches in SemOpenAlex for { <https://semopenalex.org/work/W2418743208> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2418743208 endingPage "562" @default.
- W2418743208 startingPage "556" @default.
- W2418743208 abstract "Thrombotic microangiopathy (TMA) is characterized by the presence of microangiopathic hemolytic anemia and thrombocytopenia. There are several disorders with varied etiopathogenesis, both genetic and acquired, that result in TMA. The neutrophils play an important role in inflammation and thrombosis through the formation of neutrophil extracellular traps (NETs). NETs are formed in response to a variety of stimuli including infections, chemical factors, and platelet activation. The classic TMA, thrombotic thrombocytopenic purpura (TTP) is caused by a severe deficiency of ADAMTS-13 (a disintegrin and metalloproteinase with a thrombospondin type-I motif, member 13), mostly acquired due to autoantibodies, whereas atypical hemolytic uremic syndrome (aHUS) is mostly attributed to genetic defects in complement pathway regulatory proteins. The management of these well-known disorders has evolved over the last decade. Similarly, there is also better understanding of diverse and unusual clinical presentations of both of these conditions. Since there are many other causes of TMAs, which may mimic some of the clinical features of TTP or aHUS, it is essential to thoroughly investigate each patient so that appropriate therapy can be offered. This review focuses on some important developments in understanding of etiopathogenesis, diagnosis, and treatment of more commonly encountered TMAs." @default.
- W2418743208 created "2016-06-24" @default.
- W2418743208 creator A5069666380 @default.
- W2418743208 creator A5085131046 @default.
- W2418743208 date "2015-08-15" @default.
- W2418743208 modified "2023-10-17" @default.
- W2418743208 title "Thrombosis, Microangiopathies, and Inflammation" @default.
- W2418743208 doi "https://doi.org/10.1055/s-0035-1556587" @default.
- W2418743208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26276936" @default.
- W2418743208 hasPublicationYear "2015" @default.
- W2418743208 type Work @default.
- W2418743208 sameAs 2418743208 @default.
- W2418743208 citedByCount "21" @default.
- W2418743208 countsByYear W24187432082015 @default.
- W2418743208 countsByYear W24187432082016 @default.
- W2418743208 countsByYear W24187432082017 @default.
- W2418743208 countsByYear W24187432082018 @default.
- W2418743208 countsByYear W24187432082019 @default.
- W2418743208 countsByYear W24187432082020 @default.
- W2418743208 countsByYear W24187432082021 @default.
- W2418743208 countsByYear W24187432082022 @default.
- W2418743208 countsByYear W24187432082023 @default.
- W2418743208 crossrefType "journal-article" @default.
- W2418743208 hasAuthorship W2418743208A5069666380 @default.
- W2418743208 hasAuthorship W2418743208A5085131046 @default.
- W2418743208 hasConcept C109523444 @default.
- W2418743208 hasConcept C111684460 @default.
- W2418743208 hasConcept C126322002 @default.
- W2418743208 hasConcept C134018914 @default.
- W2418743208 hasConcept C142724271 @default.
- W2418743208 hasConcept C159654299 @default.
- W2418743208 hasConcept C163764329 @default.
- W2418743208 hasConcept C167814343 @default.
- W2418743208 hasConcept C203014093 @default.
- W2418743208 hasConcept C2776513394 @default.
- W2418743208 hasConcept C2776914184 @default.
- W2418743208 hasConcept C2777878052 @default.
- W2418743208 hasConcept C2778585876 @default.
- W2418743208 hasConcept C2779134260 @default.
- W2418743208 hasConcept C2780868729 @default.
- W2418743208 hasConcept C2780921031 @default.
- W2418743208 hasConcept C2781127562 @default.
- W2418743208 hasConcept C555293320 @default.
- W2418743208 hasConcept C55728118 @default.
- W2418743208 hasConcept C71924100 @default.
- W2418743208 hasConcept C8891405 @default.
- W2418743208 hasConcept C89560881 @default.
- W2418743208 hasConceptScore W2418743208C109523444 @default.
- W2418743208 hasConceptScore W2418743208C111684460 @default.
- W2418743208 hasConceptScore W2418743208C126322002 @default.
- W2418743208 hasConceptScore W2418743208C134018914 @default.
- W2418743208 hasConceptScore W2418743208C142724271 @default.
- W2418743208 hasConceptScore W2418743208C159654299 @default.
- W2418743208 hasConceptScore W2418743208C163764329 @default.
- W2418743208 hasConceptScore W2418743208C167814343 @default.
- W2418743208 hasConceptScore W2418743208C203014093 @default.
- W2418743208 hasConceptScore W2418743208C2776513394 @default.
- W2418743208 hasConceptScore W2418743208C2776914184 @default.
- W2418743208 hasConceptScore W2418743208C2777878052 @default.
- W2418743208 hasConceptScore W2418743208C2778585876 @default.
- W2418743208 hasConceptScore W2418743208C2779134260 @default.
- W2418743208 hasConceptScore W2418743208C2780868729 @default.
- W2418743208 hasConceptScore W2418743208C2780921031 @default.
- W2418743208 hasConceptScore W2418743208C2781127562 @default.
- W2418743208 hasConceptScore W2418743208C555293320 @default.
- W2418743208 hasConceptScore W2418743208C55728118 @default.
- W2418743208 hasConceptScore W2418743208C71924100 @default.
- W2418743208 hasConceptScore W2418743208C8891405 @default.
- W2418743208 hasConceptScore W2418743208C89560881 @default.
- W2418743208 hasIssue "06" @default.
- W2418743208 hasLocation W24187432081 @default.
- W2418743208 hasLocation W24187432082 @default.
- W2418743208 hasOpenAccess W2418743208 @default.
- W2418743208 hasPrimaryLocation W24187432081 @default.
- W2418743208 hasRelatedWork W1601427375 @default.
- W2418743208 hasRelatedWork W2409863945 @default.
- W2418743208 hasRelatedWork W2418743208 @default.
- W2418743208 hasRelatedWork W2551281571 @default.
- W2418743208 hasRelatedWork W2588304086 @default.
- W2418743208 hasRelatedWork W2935328396 @default.
- W2418743208 hasRelatedWork W2998928693 @default.
- W2418743208 hasRelatedWork W3029498159 @default.
- W2418743208 hasRelatedWork W3190943721 @default.
- W2418743208 hasRelatedWork W2471765410 @default.
- W2418743208 hasVolume "41" @default.
- W2418743208 isParatext "false" @default.
- W2418743208 isRetracted "false" @default.
- W2418743208 magId "2418743208" @default.
- W2418743208 workType "article" @default.