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- W2418746629 abstract "The metabolic transformation of (-)-clausenamide, isolated from the leaves of Clausena lansium (Lour.) Skeels, was studied in vitro with phenobarbital-induced rat liver microsomal incubate containing the NADPH-generating system. The constitution of the incubation system was optimized and a RP-HPLC-DAD method was developed for the on-line analysis of (-)-clausenamide and its metabolites. The major metabolites were isolated and purified by silica gel column chromatography, preparative TLC and HPLC and their structures were determined as 6-OH clausenamide (CM1) and 5-OH clausenamide (CM2) by 1HNMR and MS." @default.
- W2418746629 created "2016-06-24" @default.
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- W2418746629 date "1998-01-01" @default.
- W2418746629 modified "2023-10-18" @default.
- W2418746629 title "[Metabolic transformation of (-)-clausenamide in rat liver microsomes]." @default.
- W2418746629 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11939071" @default.
- W2418746629 hasPublicationYear "1998" @default.
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