Matches in SemOpenAlex for { <https://semopenalex.org/work/W2418785511> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2418785511 endingPage "8" @default.
- W2418785511 startingPage "90" @default.
- W2418785511 abstract "To determine whether neutrophils are involved in airway hyperresponsiveness after ozone exposure, we studied the effect of neutrophil depletion by cyclophosphamide treatment on ozone-induced airway hyperresponsiveness in seven dogs. Airway responsiveness to inhaled methacholine was determined by modified Astograph (7 Hz oscillation method), and the numbers of neutrophils in the peripheral blood, total cell counts and differential cell counts in BALF were measured before and after ozone exposure, and after ozone exposure of dogs undergoing cyclophosphamide treatment. Ozone exposure was carried out for 2 hrs at an ozone level of 3.07 +/- 0.01 ppm (mean +/- SE), and cyclophosphamide (10 mg/kg) was given intravenously daily for five days starting six days before ozone exposure. There was a significant increase in airway responsiveness to inhaled methacholine after ozone exposure in the seven dogs (p less than 0.001), and the numbers of neutrophils in the peripheral blood and the neutrophil counts in BALF increased significantly after ozone exposure (p less than 0.01). After ozone exposure of dogs undergoing cyclophosphamide treatment, the numbers of neutrophils in the peripheral blood decreased significantly (p less than 0.001) and the neutrophil counts in BALF did not increase, but the airway responsiveness to inhaled methacholine increased significantly (p less than 0.01). There was no significant correlation between the degree of the increase in airway responsiveness and the degree of the increase in neutrophil counts in BALF after ozone exposure. These results suggest that neutrophil infiltration into the airway is not necessary for an increase in airway responsiveness after ozone exposure in dogs." @default.
- W2418785511 created "2016-06-24" @default.
- W2418785511 creator A5024508837 @default.
- W2418785511 creator A5033260263 @default.
- W2418785511 creator A5038310819 @default.
- W2418785511 creator A5042981989 @default.
- W2418785511 creator A5049905758 @default.
- W2418785511 creator A5058878517 @default.
- W2418785511 creator A5067555109 @default.
- W2418785511 creator A5067754025 @default.
- W2418785511 creator A5074744079 @default.
- W2418785511 creator A5087699141 @default.
- W2418785511 date "1990-02-01" @default.
- W2418785511 modified "2023-09-23" @default.
- W2418785511 title "[The role of neutrophils in airway hyperresponsiveness in dogs after ozone exposure]." @default.
- W2418785511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2353876" @default.
- W2418785511 hasPublicationYear "1990" @default.
- W2418785511 type Work @default.
- W2418785511 sameAs 2418785511 @default.
- W2418785511 citedByCount "1" @default.
- W2418785511 crossrefType "journal-article" @default.
- W2418785511 hasAuthorship W2418785511A5024508837 @default.
- W2418785511 hasAuthorship W2418785511A5033260263 @default.
- W2418785511 hasAuthorship W2418785511A5038310819 @default.
- W2418785511 hasAuthorship W2418785511A5042981989 @default.
- W2418785511 hasAuthorship W2418785511A5049905758 @default.
- W2418785511 hasAuthorship W2418785511A5058878517 @default.
- W2418785511 hasAuthorship W2418785511A5067555109 @default.
- W2418785511 hasAuthorship W2418785511A5067754025 @default.
- W2418785511 hasAuthorship W2418785511A5074744079 @default.
- W2418785511 hasAuthorship W2418785511A5087699141 @default.
- W2418785511 hasConcept C105922876 @default.
- W2418785511 hasConcept C121332964 @default.
- W2418785511 hasConcept C126322002 @default.
- W2418785511 hasConcept C153400128 @default.
- W2418785511 hasConcept C178790620 @default.
- W2418785511 hasConcept C185592680 @default.
- W2418785511 hasConcept C203014093 @default.
- W2418785511 hasConcept C2776178081 @default.
- W2418785511 hasConcept C2776694085 @default.
- W2418785511 hasConcept C2776755627 @default.
- W2418785511 hasConcept C2777714996 @default.
- W2418785511 hasConcept C2781260171 @default.
- W2418785511 hasConcept C3019828301 @default.
- W2418785511 hasConcept C42219234 @default.
- W2418785511 hasConcept C508106653 @default.
- W2418785511 hasConcept C71924100 @default.
- W2418785511 hasConcept C97355855 @default.
- W2418785511 hasConceptScore W2418785511C105922876 @default.
- W2418785511 hasConceptScore W2418785511C121332964 @default.
- W2418785511 hasConceptScore W2418785511C126322002 @default.
- W2418785511 hasConceptScore W2418785511C153400128 @default.
- W2418785511 hasConceptScore W2418785511C178790620 @default.
- W2418785511 hasConceptScore W2418785511C185592680 @default.
- W2418785511 hasConceptScore W2418785511C203014093 @default.
- W2418785511 hasConceptScore W2418785511C2776178081 @default.
- W2418785511 hasConceptScore W2418785511C2776694085 @default.
- W2418785511 hasConceptScore W2418785511C2776755627 @default.
- W2418785511 hasConceptScore W2418785511C2777714996 @default.
- W2418785511 hasConceptScore W2418785511C2781260171 @default.
- W2418785511 hasConceptScore W2418785511C3019828301 @default.
- W2418785511 hasConceptScore W2418785511C42219234 @default.
- W2418785511 hasConceptScore W2418785511C508106653 @default.
- W2418785511 hasConceptScore W2418785511C71924100 @default.
- W2418785511 hasConceptScore W2418785511C97355855 @default.
- W2418785511 hasIssue "2 Pt 1" @default.
- W2418785511 hasLocation W24187855111 @default.
- W2418785511 hasOpenAccess W2418785511 @default.
- W2418785511 hasPrimaryLocation W24187855111 @default.
- W2418785511 hasRelatedWork W1828905712 @default.
- W2418785511 hasRelatedWork W1928628656 @default.
- W2418785511 hasRelatedWork W1994711819 @default.
- W2418785511 hasRelatedWork W2134783117 @default.
- W2418785511 hasRelatedWork W2135602401 @default.
- W2418785511 hasRelatedWork W2150928563 @default.
- W2418785511 hasRelatedWork W2162003256 @default.
- W2418785511 hasRelatedWork W2416278417 @default.
- W2418785511 hasRelatedWork W2954619865 @default.
- W2418785511 hasRelatedWork W3136295119 @default.
- W2418785511 hasVolume "39" @default.
- W2418785511 isParatext "false" @default.
- W2418785511 isRetracted "false" @default.
- W2418785511 magId "2418785511" @default.
- W2418785511 workType "article" @default.