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- W2418888976 abstract "A multicentre, randomized, double-dummy control trial compared the efficacy of two famotidine dosage regimens for the treatment of acute gastric mucosal lesions. A total of 209 patients, aged 16-85 years, were randomized to treatment with either 10 mg famotidine twice daily or a 20 mg bedtime dose. Treatment was continued for 2 weeks unless healing occurred earlier. Endoscopy was performed before treatment and at the end of weeks 1 and 2 of treatment. Pain and haemorrhages disappeared in greater than 90% of patients after 2 weeks of treatment with either famotidine dosage. Mucosal erosions healed in more than two out of three patients by the end of the treatment period. No statistical difference was seen between the two dosage groups. Since 20 mg famotidine given at bedtime was as effective as twice daily dosing, it is recommended for the treatment of acute gastric mucosal erosions." @default.
- W2418888976 created "2016-06-24" @default.
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- W2418888976 date "1989-01-01" @default.
- W2418888976 modified "2023-09-23" @default.
- W2418888976 title "Clinical evaluation of 20 mg/day famotidine in the treatment of acute gastric mucosal lesions." @default.
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