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- W2418889211 endingPage "28" @default.
- W2418889211 startingPage "1" @default.
- W2418889211 abstract "The reproductive axis in women comprises a number of components that must function in a highly orchestrated manner for reproductive potential to be optimal. The neuroendocrine components of this axis, including the hypothalamus and the pituitary gland, are central to this system. Within the hypothalamus, the specialized neuronal system responsible for synthesizing and secreting gonadotropin-releasing hormone (GnRH) is itself modulated by a number of peptide and biogenic amine neurotransmitters that mediate feedback signals of ovarian origin. The luteinizing hormone and follicle-stimulating hormone secreting anterior pituitary gonadotropes perceive and transduce neural input in the form of GnRH, but are themselves also modulated by the ambient gonadal hormone concentrations. The authors review the physiologic relevance of the pulsatile nature of the GnRH signal, and some proposed mechanisms through which these signals are stimulated and modulated and subsequently perceived and transduced by gonadotropes." @default.
- W2418889211 created "2016-06-24" @default.
- W2418889211 creator A5004497797 @default.
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- W2418889211 date "1993-03-01" @default.
- W2418889211 modified "2023-10-18" @default.
- W2418889211 title "Normal Reproductive Neuroendocrinology in the Female" @default.
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