Matches in SemOpenAlex for { <https://semopenalex.org/work/W2419024810> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2419024810 endingPage "50" @default.
- W2419024810 startingPage "137" @default.
- W2419024810 abstract "A series of 38 patients with solid tumours (N=29) and haematological malignancies (N=9) and with suspicion of cardiotoxicity (CTX) due to antineoplastic drugs was studied. The series comprised 22 females and 16 males (mean age 52 years). The patients were examined clinically by ECG, chest X-ray and echocardiography. Seventeen patients were classified as having moderate or severe chronic CTX; 16 patients developed either arrhythmias shortly after the administration of chemotherapy (acute CTX) or arrhythmias and/or signs of myocardial dysfunction (without overt congestive heart failure) at a later date, after chemotherapy had been suspended (latent CTX). In 5 cases the suspicion of CTX could not be confirmed. Weak and non-specific symptoms such as unexplained tachycardia or coughing at night should alert the clinician and result in ECG control and further non-invasive cardiological investigations (including radionuclide angiocardiography) before additional anthracycline is administered. Chest X-ray is a very insensitive method with respect to early diagnosis of chronic CTX; in cases of doubt heart catheterization with endomyocardial biopsy should be carried out to obtain a reliable estimate of the extent of morphological damage. As anthracycline CTX may present without prominent clinical symptoms or as latent disease, one should be aware of potential precipitating factors such as volume load (during i.v. chemotherapy), surgical trauma and general anaesthesia and alcohol abuse. Further effects to lessen CTX should be made, using supposed cardio-protective substances in randomized clinical trials. Promising research on coenzyme Q10 and carnitine may usher in a new era in the prevention of anthracycline cardiotoxicity." @default.
- W2419024810 created "2016-06-24" @default.
- W2419024810 creator A5061393944 @default.
- W2419024810 creator A5065932826 @default.
- W2419024810 creator A5068237165 @default.
- W2419024810 creator A5087164454 @default.
- W2419024810 date "1986-01-01" @default.
- W2419024810 modified "2023-09-23" @default.
- W2419024810 title "Clinical and non-invasive assessment of anthracycline cardiotoxicity: perspectives on myocardial protection." @default.
- W2419024810 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3459718" @default.
- W2419024810 hasPublicationYear "1986" @default.
- W2419024810 type Work @default.
- W2419024810 sameAs 2419024810 @default.
- W2419024810 citedByCount "3" @default.
- W2419024810 countsByYear W24190248102019 @default.
- W2419024810 crossrefType "journal-article" @default.
- W2419024810 hasAuthorship W2419024810A5061393944 @default.
- W2419024810 hasAuthorship W2419024810A5065932826 @default.
- W2419024810 hasAuthorship W2419024810A5068237165 @default.
- W2419024810 hasAuthorship W2419024810A5087164454 @default.
- W2419024810 hasConcept C121608353 @default.
- W2419024810 hasConcept C126322002 @default.
- W2419024810 hasConcept C164705383 @default.
- W2419024810 hasConcept C2776694085 @default.
- W2419024810 hasConcept C2776802502 @default.
- W2419024810 hasConcept C2777385415 @default.
- W2419024810 hasConcept C2778198053 @default.
- W2419024810 hasConcept C2778233292 @default.
- W2419024810 hasConcept C2778704086 @default.
- W2419024810 hasConcept C2778797674 @default.
- W2419024810 hasConcept C2779384338 @default.
- W2419024810 hasConcept C530470458 @default.
- W2419024810 hasConcept C71924100 @default.
- W2419024810 hasConceptScore W2419024810C121608353 @default.
- W2419024810 hasConceptScore W2419024810C126322002 @default.
- W2419024810 hasConceptScore W2419024810C164705383 @default.
- W2419024810 hasConceptScore W2419024810C2776694085 @default.
- W2419024810 hasConceptScore W2419024810C2776802502 @default.
- W2419024810 hasConceptScore W2419024810C2777385415 @default.
- W2419024810 hasConceptScore W2419024810C2778198053 @default.
- W2419024810 hasConceptScore W2419024810C2778233292 @default.
- W2419024810 hasConceptScore W2419024810C2778704086 @default.
- W2419024810 hasConceptScore W2419024810C2778797674 @default.
- W2419024810 hasConceptScore W2419024810C2779384338 @default.
- W2419024810 hasConceptScore W2419024810C530470458 @default.
- W2419024810 hasConceptScore W2419024810C71924100 @default.
- W2419024810 hasIssue "2" @default.
- W2419024810 hasLocation W24190248101 @default.
- W2419024810 hasOpenAccess W2419024810 @default.
- W2419024810 hasPrimaryLocation W24190248101 @default.
- W2419024810 hasRelatedWork W1995866608 @default.
- W2419024810 hasRelatedWork W2128669491 @default.
- W2419024810 hasRelatedWork W2394557802 @default.
- W2419024810 hasRelatedWork W2401204292 @default.
- W2419024810 hasRelatedWork W2404305485 @default.
- W2419024810 hasRelatedWork W2419024810 @default.
- W2419024810 hasRelatedWork W2939437929 @default.
- W2419024810 hasRelatedWork W3012405276 @default.
- W2419024810 hasRelatedWork W3110485444 @default.
- W2419024810 hasRelatedWork W4235972174 @default.
- W2419024810 hasVolume "6" @default.
- W2419024810 isParatext "false" @default.
- W2419024810 isRetracted "false" @default.
- W2419024810 magId "2419024810" @default.
- W2419024810 workType "article" @default.