Matches in SemOpenAlex for { <https://semopenalex.org/work/W2419028178> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2419028178 endingPage "8" @default.
- W2419028178 startingPage "1855" @default.
- W2419028178 abstract "Haemotoxicity is usually the primary and dose-limiting side-effect of docetaxel (TXT) a semysyntetic analogue of paclitaxel which has acquired an important role in anticancer treatment. This research presents the results of an in vitro toxicity study of TXT on myeloid progenitors obtained from healthy volunteers and assayed as CFU-GM. Peripheral blood mononucleated non-adherent cells (MNAC) were incubated for 24 h at standard conditions with increasing concentrations of TXT and then cultured for CFU-GM assay. At every concentration severe CFU-GM growth inhibition was observed. In a second set of experiments MNAC were sequentially exposed to TXT and then to doxorubicin or cisplatin or vinorelbine or etoposide at appropriate concentrations. In a third set the sequence of exposure was reversed. No difference of CFU-GM growth inhibition was observed between the alternate sequences. These findings suggest that the toxicity on CFU-GM in vitro growth of TXT combinations with other anticancer drugs is sequence-independent." @default.
- W2419028178 created "2016-06-24" @default.
- W2419028178 creator A5010890043 @default.
- W2419028178 creator A5015848006 @default.
- W2419028178 creator A5016522312 @default.
- W2419028178 creator A5018858868 @default.
- W2419028178 creator A5039913598 @default.
- W2419028178 creator A5075551377 @default.
- W2419028178 date "1999-09-02" @default.
- W2419028178 modified "2023-09-23" @default.
- W2419028178 title "Effects of docetaxel on the in vitro growth of human myeloid progenitors." @default.
- W2419028178 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10470127" @default.
- W2419028178 hasPublicationYear "1999" @default.
- W2419028178 type Work @default.
- W2419028178 sameAs 2419028178 @default.
- W2419028178 citedByCount "2" @default.
- W2419028178 crossrefType "journal-article" @default.
- W2419028178 hasAuthorship W2419028178A5010890043 @default.
- W2419028178 hasAuthorship W2419028178A5015848006 @default.
- W2419028178 hasAuthorship W2419028178A5016522312 @default.
- W2419028178 hasAuthorship W2419028178A5018858868 @default.
- W2419028178 hasAuthorship W2419028178A5039913598 @default.
- W2419028178 hasAuthorship W2419028178A5075551377 @default.
- W2419028178 hasConcept C126322002 @default.
- W2419028178 hasConcept C185592680 @default.
- W2419028178 hasConcept C201750760 @default.
- W2419028178 hasConcept C202751555 @default.
- W2419028178 hasConcept C2776694085 @default.
- W2419028178 hasConcept C2777292972 @default.
- W2419028178 hasConcept C2778119113 @default.
- W2419028178 hasConcept C2778239845 @default.
- W2419028178 hasConcept C2779282312 @default.
- W2419028178 hasConcept C2779707156 @default.
- W2419028178 hasConcept C2780350996 @default.
- W2419028178 hasConcept C2781190966 @default.
- W2419028178 hasConcept C2781303535 @default.
- W2419028178 hasConcept C28328180 @default.
- W2419028178 hasConcept C29730261 @default.
- W2419028178 hasConcept C502942594 @default.
- W2419028178 hasConcept C55493867 @default.
- W2419028178 hasConcept C71924100 @default.
- W2419028178 hasConcept C86803240 @default.
- W2419028178 hasConcept C95444343 @default.
- W2419028178 hasConcept C98274493 @default.
- W2419028178 hasConceptScore W2419028178C126322002 @default.
- W2419028178 hasConceptScore W2419028178C185592680 @default.
- W2419028178 hasConceptScore W2419028178C201750760 @default.
- W2419028178 hasConceptScore W2419028178C202751555 @default.
- W2419028178 hasConceptScore W2419028178C2776694085 @default.
- W2419028178 hasConceptScore W2419028178C2777292972 @default.
- W2419028178 hasConceptScore W2419028178C2778119113 @default.
- W2419028178 hasConceptScore W2419028178C2778239845 @default.
- W2419028178 hasConceptScore W2419028178C2779282312 @default.
- W2419028178 hasConceptScore W2419028178C2779707156 @default.
- W2419028178 hasConceptScore W2419028178C2780350996 @default.
- W2419028178 hasConceptScore W2419028178C2781190966 @default.
- W2419028178 hasConceptScore W2419028178C2781303535 @default.
- W2419028178 hasConceptScore W2419028178C28328180 @default.
- W2419028178 hasConceptScore W2419028178C29730261 @default.
- W2419028178 hasConceptScore W2419028178C502942594 @default.
- W2419028178 hasConceptScore W2419028178C55493867 @default.
- W2419028178 hasConceptScore W2419028178C71924100 @default.
- W2419028178 hasConceptScore W2419028178C86803240 @default.
- W2419028178 hasConceptScore W2419028178C95444343 @default.
- W2419028178 hasConceptScore W2419028178C98274493 @default.
- W2419028178 hasIssue "3A" @default.
- W2419028178 hasLocation W24190281781 @default.
- W2419028178 hasOpenAccess W2419028178 @default.
- W2419028178 hasPrimaryLocation W24190281781 @default.
- W2419028178 hasRelatedWork W1969285468 @default.
- W2419028178 hasRelatedWork W2013926406 @default.
- W2419028178 hasRelatedWork W2014550317 @default.
- W2419028178 hasRelatedWork W2058661138 @default.
- W2419028178 hasRelatedWork W222594567 @default.
- W2419028178 hasRelatedWork W2406439626 @default.
- W2419028178 hasRelatedWork W2412969155 @default.
- W2419028178 hasRelatedWork W2413859356 @default.
- W2419028178 hasRelatedWork W2419028178 @default.
- W2419028178 hasRelatedWork W2753894119 @default.
- W2419028178 hasVolume "19" @default.
- W2419028178 isParatext "false" @default.
- W2419028178 isRetracted "false" @default.
- W2419028178 magId "2419028178" @default.
- W2419028178 workType "article" @default.