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- W2419042258 abstract "T cell antigen-receptor signal transduction is helped by LAT (linker for activation of T cells), SLP-76 (SH-2 containing leukocyte protein 76), and Itk (inducible T cell kinase). With the help of CD3, CD4 or CD8, reorganization of the cytoskeleton as well as transcription activation can be carried out. This improves the TCR signaling as a whole. With the presence and balance of kinase and phosphate activities, signal transduction can be regulated but with thymic isoform lacking, signal transduction is defective. This micro review will discuss how T cell antigen receptor signal transduction works as well as why with a balance of kinase and phosphate it is regulated but with a lack of thymic isoform it is defective." @default.
- W2419042258 created "2016-06-24" @default.
- W2419042258 creator A5027805455 @default.
- W2419042258 date "2012-12-03" @default.
- W2419042258 modified "2023-09-28" @default.
- W2419042258 title "The regulation and defectiveness of T cell antigen-receptor signal transduction with the help of kinase and phosphatase for regulation and defectiveness when lacking thymic isoform of p59 (fyn)" @default.
- W2419042258 hasPublicationYear "2012" @default.
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