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- W2419052800 abstract "Context: Drug-resistant bacterial infections cause considerable patient mortality and morbidity. The annual frequency of deaths from methicillin-resistant Staphylococcus aureus (MRSA) has surpassed those caused by human immunodeficiency virus/acquired immune deficiency syndrome. The antimicrobial peptides (AMPs), plant essential oils (EOs) and their combinations have proven to be quite effective in killing a wide selection of bacterial pathogens including MRSA.Objectives: This review summarizes the studies in the use of AMPs, plant EOs and their combinations for coping with MRSA bacteria, and to formulate new prospects for future studies on this topic.Methods: The sources of scientific literature such as PubMed, library search, Google Scholar, Science Direct and electronic databases such as ‘The Antimicrobial Peptide Database’, ‘Collection of Anti-Microbial Peptides’ and ‘YADAMP’. Physicochemical data of anti-MRSA peptides were determined by Scientific DataBase Maker software.Results: Of the 118 peptides, 88 exhibited an activity against MRSA with the highest activity of minimum inhibitory concentration values. Various plant EOs have been effective against MRSA. Remarkably, lemongrass EOs completely inhibited all MRSA growth on the plate. Lemon myrtle, Mountain savory, Cinnamon bark and Melissa EOs showed a significant inhibition.Conclusion: Several of these AMPs, EOs and their combinations were effective against MRSA. Their activities have implications for the development of new drugs for medical use." @default.
- W2419052800 created "2016-06-24" @default.
- W2419052800 creator A5046137859 @default.
- W2419052800 creator A5053299807 @default.
- W2419052800 creator A5055946282 @default.
- W2419052800 creator A5080963590 @default.
- W2419052800 creator A5081917156 @default.
- W2419052800 date "2016-06-01" @default.
- W2419052800 modified "2023-09-28" @default.
- W2419052800 title "Inhibition of methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) by antimicrobial peptides (AMPs) and plant essential oils" @default.
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- W2419052800 doi "https://doi.org/10.1080/13880209.2016.1190763" @default.
- W2419052800 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27246787" @default.
- W2419052800 hasPublicationYear "2016" @default.