FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2419223036> ?p ?o ?g. }

• W2419223036 abstract "The molecular surface imprinted graft copolymer of chitosan with methyl methacrylate (MIP-CS-g-PMMA) were prepared by free radical polymerization with 5-fluorouracil (5-FU) as the template molecule using initiator of ammonium persulfate as adsorption system. MIPs were characterized by FTIR, X-ray diffraction, thermo-gravimetric analysis, (1)H NMR and SEM. The mechanism of graft copolymerization and factors affected graft reaction were studied in details, and the optimum reaction conditions (to the highest %G and %E as the standard) were obtained at [MMA] 1.2 mol/L, [Chitosan] 16.67 mol/L, [initiator] 0.0062 mol/L, temperature 60 °C and reaction time 7 h. MIPs exhibited high recognition selectivity and excellent combining affinity to template molecular. The in vitro release of the 5-FU was highly pH-dependent and time delayed. The release behavior showed that the drugs did not release in simulated gastric fluid (pH = 1.0), and the drug release was small in the simulated small intestinal fluid (pH = 6.8), and drug abrupt release will be produced in the simulated colon fluid (pH = 7.4), indicating excellent colon-specific drug delivery behavior." @default.
• W2419223036 created "2016-06-24" @default.
• W2419223036 creator A5005895775 @default.
• W2419223036 creator A5005948191 @default.
• W2419223036 creator A5072351882 @default.
• W2419223036 creator A5088002896 @default.
• W2419223036 date "2016-02-19" @default.
• W2419223036 modified "2023-10-09" @default.
• W2419223036 title "Surface Molecularly Imprinted Polymer of Chitosan Grafted Poly(methyl methacrylate) for 5-Fluorouracil and Controlled Release" @default.
• W2419223036 cites W1963491792 @default.
• W2419223036 cites W1966288407 @default.
• W2419223036 cites W1967010706 @default.
• W2419223036 cites W1970574307 @default.
• W2419223036 cites W1976436086 @default.
• W2419223036 cites W1980656078 @default.
• W2419223036 cites W1981028981 @default.
• W2419223036 cites W1983315987 @default.
• W2419223036 cites W1999346310 @default.
• W2419223036 cites W2000919795 @default.
• W2419223036 cites W2014256613 @default.
• W2419223036 cites W2015892042 @default.
• W2419223036 cites W2021518132 @default.
• W2419223036 cites W2026423808 @default.
• W2419223036 cites W2027050898 @default.
• W2419223036 cites W2029450294 @default.
• W2419223036 cites W2031246464 @default.
• W2419223036 cites W2035918494 @default.
• W2419223036 cites W2039419770 @default.
• W2419223036 cites W2039716629 @default.
• W2419223036 cites W2046109204 @default.
• W2419223036 cites W2054305000 @default.
• W2419223036 cites W2061738193 @default.
• W2419223036 cites W2062068535 @default.
• W2419223036 cites W2066454659 @default.
• W2419223036 cites W2076774132 @default.
• W2419223036 cites W2077814061 @default.
• W2419223036 cites W2077897304 @default.
• W2419223036 cites W2081321019 @default.
• W2419223036 cites W2084830943 @default.
• W2419223036 cites W2087778274 @default.
• W2419223036 cites W2095107272 @default.
• W2419223036 cites W2119536455 @default.
• W2419223036 cites W2120812757 @default.
• W2419223036 cites W2141736809 @default.
• W2419223036 cites W2143634523 @default.
• W2419223036 cites W2145496621 @default.
• W2419223036 cites W2155055324 @default.
• W2419223036 doi "https://doi.org/10.1038/srep21409" @default.
• W2419223036 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4759818" @default.
• W2419223036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26892676" @default.
• W2419223036 hasPublicationYear "2016" @default.
• W2419223036 type Work @default.
• W2419223036 sameAs 2419223036 @default.
• W2419223036 citedByCount "57" @default.
• W2419223036 countsByYear W24192230362016 @default.
• W2419223036 countsByYear W24192230362017 @default.
• W2419223036 countsByYear W24192230362018 @default.
• W2419223036 countsByYear W24192230362019 @default.
• W2419223036 countsByYear W24192230362020 @default.
• W2419223036 countsByYear W24192230362021 @default.
• W2419223036 countsByYear W24192230362022 @default.
• W2419223036 countsByYear W24192230362023 @default.
• W2419223036 crossrefType "journal-article" @default.
• W2419223036 hasAuthorship W2419223036A5005895775 @default.
• W2419223036 hasAuthorship W2419223036A5005948191 @default.
• W2419223036 hasAuthorship W2419223036A5072351882 @default.
• W2419223036 hasAuthorship W2419223036A5088002896 @default.
• W2419223036 hasBestOaLocation W24192230361 @default.
• W2419223036 hasConcept C118792377 @default.
• W2419223036 hasConcept C127413603 @default.
• W2419223036 hasConcept C132050475 @default.
• W2419223036 hasConcept C13965031 @default.
• W2419223036 hasConcept C150394285 @default.
• W2419223036 hasConcept C15920480 @default.
• W2419223036 hasConcept C160892712 @default.
• W2419223036 hasConcept C161790260 @default.
• W2419223036 hasConcept C162602672 @default.
• W2419223036 hasConcept C178790620 @default.
• W2419223036 hasConcept C185592680 @default.
• W2419223036 hasConcept C188027245 @default.
• W2419223036 hasConcept C2777935641 @default.
• W2419223036 hasConcept C2779732960 @default.
• W2419223036 hasConcept C2780023803 @default.
• W2419223036 hasConcept C39442485 @default.
• W2419223036 hasConcept C42360764 @default.
• W2419223036 hasConcept C44228677 @default.
• W2419223036 hasConcept C521977710 @default.
• W2419223036 hasConceptScore W2419223036C118792377 @default.
• W2419223036 hasConceptScore W2419223036C127413603 @default.
• W2419223036 hasConceptScore W2419223036C132050475 @default.
• W2419223036 hasConceptScore W2419223036C13965031 @default.
• W2419223036 hasConceptScore W2419223036C150394285 @default.
• W2419223036 hasConceptScore W2419223036C15920480 @default.
• W2419223036 hasConceptScore W2419223036C160892712 @default.
• W2419223036 hasConceptScore W2419223036C161790260 @default.
• W2419223036 hasConceptScore W2419223036C162602672 @default.
• W2419223036 hasConceptScore W2419223036C178790620 @default.
• W2419223036 hasConceptScore W2419223036C185592680 @default.
• W2419223036 hasConceptScore W2419223036C188027245 @default.
• W2419223036 hasConceptScore W2419223036C2777935641 @default.

• next