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- W2419249600 abstract "A plasma assay for paracetamol by HPLC is described. Paracetamol is extracted with diethyl ether in the presence of an internal standard, beta- hydroxyethyltheophylline . The extracts are analysed using reversed phase chromatography (Radial Pak C18 column), the mobile phase consisting of a buffer mixture of 0.01 mol/l acetate (pH 4)-acetonitrile (920-80, v/v). The method is simple, rapid, precise and sensitive (lower level of sensitivity 0.13 mumol/l). It was used in a pharmacokinetic study in twelve volunteers." @default.
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- W2419249600 date "1984-01-01" @default.
- W2419249600 modified "2023-09-26" @default.
- W2419249600 title "[Plasma determination of paracetamol using high performance liquid chromatography. Application to a pharmacokinetic study]." @default.
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