FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2419251031> ?p ?o ?g. }

• W2419251031 endingPage "712" @default.
• W2419251031 startingPage "703" @default.
• W2419251031 abstract "In support of the Integrated Risk Information System (IRIS), the U.S. Environmental Protection Agency (EPA) has evaluated the human health hazards of biphenyl exposure.We review key findings and scientific issues regarding expected human health effects of biphenyl.Scientific literature from 1926 through September 2012 was critically evaluated to identify potential human health hazards associated with biphenyl exposure. Key issues related to the carcinogenicity and noncancer health hazards of biphenyl were examined based on evidence from experimental animal bioassays and mechanistic studies.Systematic consideration of experimental animal studies of oral biphenyl exposure took into account the variety of study designs (e.g., study sizes, exposure levels, and exposure durations) to reconcile differing reported results. The available mechanistic and toxicokinetic evidence supports the hypothesis that male rat urinary bladder tumors arise through urinary bladder calculi formation but is insufficient to hypothesize a mode of action for liver tumors in female mice. Biphenyl and its metabolites may induce genetic damage, but a role for genotoxicity in biphenyl-induced carcinogenicity has not been established.The available health effects data for biphenyl provides suggestive evidence for carcinogenicity in humans, based on increased incidences of male rat urinary bladder tumors at high exposure levels and on female mouse liver tumors. Kidney toxicity is also a potential human health hazard of biphenyl exposure.Li Z, Hogan KA, Cai C, Rieth S. 2016. Human health effects of biphenyl: key findings and scientific issues. Environ Health Perspect 124:703-712; http://dx.doi.org/10.1289/ehp.1509730." @default.
• W2419251031 created "2016-06-24" @default.
• W2419251031 creator A5044109032 @default.
• W2419251031 creator A5060335470 @default.
• W2419251031 creator A5060820385 @default.
• W2419251031 creator A5073931083 @default.
• W2419251031 date "2016-06-01" @default.
• W2419251031 modified "2023-10-12" @default.
• W2419251031 title "Human Health Effects of Biphenyl: Key Findings and Scientific Issues" @default.
• W2419251031 cites W10203075 @default.
• W2419251031 cites W1547211887 @default.
• W2419251031 cites W1548355813 @default.
• W2419251031 cites W1911132161 @default.
• W2419251031 cites W1915410916 @default.
• W2419251031 cites W1950516314 @default.
• W2419251031 cites W1965745155 @default.
• W2419251031 cites W1969370511 @default.
• W2419251031 cites W1970870682 @default.
• W2419251031 cites W1972505674 @default.
• W2419251031 cites W1975039291 @default.
• W2419251031 cites W1983031036 @default.
• W2419251031 cites W1983349814 @default.
• W2419251031 cites W1985443295 @default.
• W2419251031 cites W1986837154 @default.
• W2419251031 cites W1987322594 @default.
• W2419251031 cites W1987367978 @default.
• W2419251031 cites W1987849240 @default.
• W2419251031 cites W1988391244 @default.
• W2419251031 cites W1989080650 @default.
• W2419251031 cites W1997747008 @default.
• W2419251031 cites W1998030924 @default.
• W2419251031 cites W1998600050 @default.
• W2419251031 cites W2003270593 @default.
• W2419251031 cites W2003695504 @default.
• W2419251031 cites W2007291959 @default.
• W2419251031 cites W2008530743 @default.
• W2419251031 cites W2012674820 @default.
• W2419251031 cites W2012743909 @default.
• W2419251031 cites W2016293030 @default.
• W2419251031 cites W2019193439 @default.
• W2419251031 cites W2021103007 @default.
• W2419251031 cites W2023400605 @default.
• W2419251031 cites W2025536549 @default.
• W2419251031 cites W2028760046 @default.
• W2419251031 cites W2028773528 @default.
• W2419251031 cites W2028888988 @default.
• W2419251031 cites W2029389380 @default.
• W2419251031 cites W2029774871 @default.
• W2419251031 cites W2029813269 @default.
• W2419251031 cites W2031286860 @default.
• W2419251031 cites W2032751799 @default.
• W2419251031 cites W2042804598 @default.
• W2419251031 cites W2043484930 @default.
• W2419251031 cites W2052578902 @default.
• W2419251031 cites W2053412904 @default.
• W2419251031 cites W2056090202 @default.
• W2419251031 cites W2062187854 @default.
• W2419251031 cites W2064913242 @default.
• W2419251031 cites W2065584595 @default.
• W2419251031 cites W2067653855 @default.
• W2419251031 cites W2069866944 @default.
• W2419251031 cites W2074979272 @default.
• W2419251031 cites W2079250017 @default.
• W2419251031 cites W2088584693 @default.
• W2419251031 cites W2090419653 @default.
• W2419251031 cites W2090626482 @default.
• W2419251031 cites W2099720809 @default.
• W2419251031 cites W2104964105 @default.
• W2419251031 cites W2118561897 @default.
• W2419251031 cites W2119809337 @default.
• W2419251031 cites W2147761499 @default.
• W2419251031 cites W2155920295 @default.
• W2419251031 cites W2165163523 @default.
• W2419251031 cites W2169105152 @default.
• W2419251031 cites W2272757539 @default.
• W2419251031 cites W2327510306 @default.
• W2419251031 cites W2329062053 @default.
• W2419251031 cites W2337308115 @default.
• W2419251031 cites W2342716173 @default.
• W2419251031 cites W2400885497 @default.
• W2419251031 cites W2413020136 @default.
• W2419251031 cites W2421667599 @default.
• W2419251031 cites W2422355815 @default.
• W2419251031 cites W2475172751 @default.
• W2419251031 cites W4210959301 @default.
• W2419251031 cites W4211206272 @default.
• W2419251031 cites W4243770760 @default.
• W2419251031 cites W2079576968 @default.
• W2419251031 doi "https://doi.org/10.1289/ehp.1509730" @default.
• W2419251031 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4892917" @default.
• W2419251031 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26529796" @default.
• W2419251031 hasPublicationYear "2016" @default.
• W2419251031 type Work @default.
• W2419251031 sameAs 2419251031 @default.
• W2419251031 citedByCount "12" @default.
• W2419251031 countsByYear W24192510312018 @default.
• W2419251031 countsByYear W24192510312019 @default.
• W2419251031 countsByYear W24192510312021 @default.

• next