Matches in SemOpenAlex for { <https://semopenalex.org/work/W2419256674> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2419256674 endingPage "434" @default.
- W2419256674 startingPage "429" @default.
- W2419256674 abstract "OBJECTIVES The objective of this study was to retrospectively evaluate response and outcome of dogs with multicentric lymphoma treated with single‐agent vinblastine as a second rescue. METHODS Medical records from 39 client‐owned dogs receiving vinblastine rescue treatment (having relapsed on or following completion of UW ‐Madison and CCNU /L‐asparaginase protocols), between 2005 and 2014, were reviewed for information regarding clinical presentation, diagnostic testing, drug dosage, number of treatments, side effects, response and outcome. RESULTS The median starting dose of vinblastine was 2·6 mg/m 2 (1·7 to 2·8 mg/m 2 ), administered weekly until disease progression. Of the 39 dogs treated, 3 dogs (7·7%) achieved a complete remission, 7 dogs (17·9%) achieved a partial response, 18 dogs (46·2%) maintained stable disease and 11 (28·2%) had progressive disease. Ten dogs (25·6%) developed a grade III or IV neutropenia, and 4 dogs (10·3%) developed grade III or IV thrombocytopenia (one dog in both categories). After starting vinblastine, the median progression‐free survival was 29·5 days (0 to 77 days) and overall median survival time was 46 days (4 to 250 days). Duration of first remission was identified as a positive predictor of outcome. CLINICAL SIGNIFICANCE Single‐agent vinblastine is well tolerated in dogs with relapsed or refractory lymphoma. Responses were incomplete and short‐lasting." @default.
- W2419256674 created "2016-06-24" @default.
- W2419256674 creator A5053442105 @default.
- W2419256674 creator A5067814291 @default.
- W2419256674 creator A5081539515 @default.
- W2419256674 date "2016-06-01" @default.
- W2419256674 modified "2023-09-27" @default.
- W2419256674 title "Vinblastine as a second rescue for the treatment of canine multicentric lymphoma in 39 cases (2005 to 2014)" @default.
- W2419256674 cites W1582146330 @default.
- W2419256674 cites W1723795072 @default.
- W2419256674 cites W1917082564 @default.
- W2419256674 cites W1939376872 @default.
- W2419256674 cites W1985498995 @default.
- W2419256674 cites W1992052906 @default.
- W2419256674 cites W2007326663 @default.
- W2419256674 cites W2009738666 @default.
- W2419256674 cites W2010132150 @default.
- W2419256674 cites W2011245851 @default.
- W2419256674 cites W2017607493 @default.
- W2419256674 cites W2019607817 @default.
- W2419256674 cites W2023548901 @default.
- W2419256674 cites W2031127532 @default.
- W2419256674 cites W2035769780 @default.
- W2419256674 cites W2078574394 @default.
- W2419256674 cites W2078978698 @default.
- W2419256674 cites W2105094532 @default.
- W2419256674 cites W2146647803 @default.
- W2419256674 cites W2585414498 @default.
- W2419256674 cites W4205388838 @default.
- W2419256674 cites W4245167574 @default.
- W2419256674 cites W4247428402 @default.
- W2419256674 doi "https://doi.org/10.1111/jsap.12500" @default.
- W2419256674 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27251593" @default.
- W2419256674 hasPublicationYear "2016" @default.
- W2419256674 type Work @default.
- W2419256674 sameAs 2419256674 @default.
- W2419256674 citedByCount "12" @default.
- W2419256674 countsByYear W24192566742017 @default.
- W2419256674 countsByYear W24192566742018 @default.
- W2419256674 countsByYear W24192566742019 @default.
- W2419256674 countsByYear W24192566742021 @default.
- W2419256674 countsByYear W24192566742023 @default.
- W2419256674 crossrefType "journal-article" @default.
- W2419256674 hasAuthorship W2419256674A5053442105 @default.
- W2419256674 hasAuthorship W2419256674A5067814291 @default.
- W2419256674 hasAuthorship W2419256674A5081539515 @default.
- W2419256674 hasBestOaLocation W24192566741 @default.
- W2419256674 hasConcept C121332964 @default.
- W2419256674 hasConcept C126322002 @default.
- W2419256674 hasConcept C141071460 @default.
- W2419256674 hasConcept C142424586 @default.
- W2419256674 hasConcept C195910791 @default.
- W2419256674 hasConcept C2776694085 @default.
- W2419256674 hasConcept C2777063308 @default.
- W2419256674 hasConcept C2777132456 @default.
- W2419256674 hasConcept C2778822529 @default.
- W2419256674 hasConcept C2779338263 @default.
- W2419256674 hasConcept C2908752941 @default.
- W2419256674 hasConcept C71924100 @default.
- W2419256674 hasConcept C87355193 @default.
- W2419256674 hasConcept C90924648 @default.
- W2419256674 hasConceptScore W2419256674C121332964 @default.
- W2419256674 hasConceptScore W2419256674C126322002 @default.
- W2419256674 hasConceptScore W2419256674C141071460 @default.
- W2419256674 hasConceptScore W2419256674C142424586 @default.
- W2419256674 hasConceptScore W2419256674C195910791 @default.
- W2419256674 hasConceptScore W2419256674C2776694085 @default.
- W2419256674 hasConceptScore W2419256674C2777063308 @default.
- W2419256674 hasConceptScore W2419256674C2777132456 @default.
- W2419256674 hasConceptScore W2419256674C2778822529 @default.
- W2419256674 hasConceptScore W2419256674C2779338263 @default.
- W2419256674 hasConceptScore W2419256674C2908752941 @default.
- W2419256674 hasConceptScore W2419256674C71924100 @default.
- W2419256674 hasConceptScore W2419256674C87355193 @default.
- W2419256674 hasConceptScore W2419256674C90924648 @default.
- W2419256674 hasIssue "8" @default.
- W2419256674 hasLocation W24192566741 @default.
- W2419256674 hasLocation W24192566742 @default.
- W2419256674 hasOpenAccess W2419256674 @default.
- W2419256674 hasPrimaryLocation W24192566741 @default.
- W2419256674 hasRelatedWork W2007770896 @default.
- W2419256674 hasRelatedWork W2068573191 @default.
- W2419256674 hasRelatedWork W2135788809 @default.
- W2419256674 hasRelatedWork W2378820476 @default.
- W2419256674 hasRelatedWork W2418393430 @default.
- W2419256674 hasRelatedWork W2428376671 @default.
- W2419256674 hasRelatedWork W2761272722 @default.
- W2419256674 hasRelatedWork W280698033 @default.
- W2419256674 hasRelatedWork W3138994228 @default.
- W2419256674 hasRelatedWork W3156045381 @default.
- W2419256674 hasVolume "57" @default.
- W2419256674 isParatext "false" @default.
- W2419256674 isRetracted "false" @default.
- W2419256674 magId "2419256674" @default.
- W2419256674 workType "article" @default.